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372770 HBDDE - CAS 154675-18-0 - Calbiochem

A cell-permeable protein kinase C (PKC) inhibitor that selectively inhibits PKC&alpha and PKCγ over PKCδ, βI, and βII isozymes in in vitro assays.

HBDDE - CAS 154675-18-0 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: 2,2ʹ,3,3ʹ,4,4ʹ-Hexahydroxy-1,1ʹ-biphenyl-6,6ʹ-dimethanol Dimethyl Ether

Primary Target: PKCα
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372770
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
154675-18-0C₁₆H₁₈O₈

価格＆在庫状況

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372770-1MGCN
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      Description
      OverviewA cell-permeable protein kinase C (PKC) inhibitor that selectively inhibits PKCα (IC50 = 43 µM) and PKCγ (IC50 = 50 µM) over PKCδ, βI, and βII isozymes in in vitro assays. Reported to induce apoptosis in rodent cerebellar granule neurons.
      Catalogue Number372770
      Brand Family Calbiochem®
      Synonyms2,2ʹ,3,3ʹ,4,4ʹ-Hexahydroxy-1,1ʹ-biphenyl-6,6ʹ-dimethanol Dimethyl Ether
      References
      ReferencesMathur, A., and Vallano, M.L. 2000. Biochem. Pharmacol. 60, 809.
      Kashiwada, Y., et al. 1994. J. Med. Chem. 37, 195.
      Product Information
      CAS number154675-18-0
      ATP CompetitiveN
      FormOrange solid
      Hill FormulaC₁₆H₁₈O₈
      Chemical formulaC₁₆H₁₈O₈
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKCα
      Primary Target IC<sub>50</sub>43 µM against PKCα
      Purity≥95% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      372770-1MGCN 04055977212884

      Documentation

      HBDDE - CAS 154675-18-0 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      HBDDE - CAS 154675-18-0 - Calbiochem 試験成績書（CoA）

      タイトルロット番号
      372770

      参考資料

      参考資料の概要
      Mathur, A., and Vallano, M.L. 2000. Biochem. Pharmacol. 60, 809.
      Kashiwada, Y., et al. 1994. J. Med. Chem. 37, 195.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-December-2018 JSW
      Synonyms2,2ʹ,3,3ʹ,4,4ʹ-Hexahydroxy-1,1ʹ-biphenyl-6,6ʹ-dimethanol Dimethyl Ether
      DescriptionProtein kinase C (PKC) inhibitor. Selectively inhibits PKCα (IC50 = 43 µM) and PKCγ (IC50 = 50 µM) over PKCδ, βI and βII isozymes.
      FormOrange solid
      CAS number154675-18-0
      Chemical formulaC₁₆H₁₈O₈
      Structure formulaStructure formula
      Purity≥95% by TLC
      SolubilityDMSO (5 mg/ml), Ethanol (1 mg/ml), or warm H₂O (1 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesMathur, A., and Vallano, M.L. 2000. Biochem. Pharmacol. 60, 809.
      Kashiwada, Y., et al. 1994. J. Med. Chem. 37, 195.