H2A.X Phosphorylation Assay Kit (Chemiluminescence Detection)

"Epigenetics describes heritable changes in gene expression caused by non-genetic mechanisms instead of by alterations in DNA sequence. These changes can be cell- or tissue-specific, and can be passed on to multiple generations. Epigenetic regulation enriches DNAbased information, allowing a cell to vary its response across diverse biological and environmental contexts. Although epigenetic mechanisms are primarily centered in the nucleus, these mechanisms can be induced by environmental signals such as hormones, nutrients, stress, and cellular damage, pointing to the involvement of cytoplasmic and extracellular factors in epigenetic regulation."

Evading Apoptosis: Cell Based Assays. As leaders in cancer research, EMD Millipore scientists have developed a wide range of assays and reagents to help uncover apoptosis mechanisms and possible ways to induce apoptosis in tumor cells for therapeutic benefit.