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371725 GPR43 (FFA2) Agonist - CAS 1208552-99-1 - Calbiochem

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371725
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概要

Replacement Information

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CAS #Empirical Formula
1208552-99-1C₂₁H₂₁ClN₂OS

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371725-10MGCN
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      Description
      OverviewA phenylacetamide compound that acts as an allosteric agonist of FFA2 (GPR43), demonstrating a left-shifted acetate dose response (IC50 = 0.7 µM) and 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays.
      Catalogue Number371725
      Brand Family Calbiochem®
      Synonyms(S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide
      References
      ReferencesWang, Y., et al. 2009. Bioorg. Med. Chem. Lett. 20, 493.
      Product Information
      CAS number1208552-99-1
      FormWhite solid
      Hill FormulaC₂₁H₂₁ClN₂OS
      Chemical formulaC₂₁H₂₁ClN₂OS
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationGPR43 (FFA2) Agonist is an allosteric agonist of FFA2 (GPR43). Displays a left-shifted acetate dose response (IC50 = 0.7 µM) & 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays.
      Biological Information
      Purity>98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      371725-10MGCN 04055977213270

      Documentation

      GPR43 (FFA2) Agonist - CAS 1208552-99-1 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート((M)SDS) 

      GPR43 (FFA2) Agonist - CAS 1208552-99-1 - Calbiochem 試験成績書(CoA)

      タイトルロット番号
      371725

      参考資料

      参考資料の概要
      Wang, Y., et al. 2009. Bioorg. Med. Chem. Lett. 20, 493.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-June-2015 JSW
      Synonyms(S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide
      DescriptionA phenylacetamide compound that acts as an allosteric agonist of FFA2 (GPR43), demonstrating a left-shifted acetate dose response (IC50 = 0.7 µM) and 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays.
      FormWhite solid
      CAS number1208552-99-1
      Chemical formulaC₂₁H₂₁ClN₂OS
      Structure formulaStructure formula
      Purity>98% by HPLC
      SolubilityDMSO (50 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesWang, Y., et al. 2009. Bioorg. Med. Chem. Lett. 20, 493.