Millipore Sigma Vibrant Logo

AG252 GAD, control peptide for AB1511

View This Product on Sigma-Aldrich
AG252
50 µg  
価格が見つかりません
Minimum Quantity needs to be mulitiple of
Maximum Quantity is
弊社照会 詳細を表示 
値引
()
 
弊社照会
現在国内在庫なし
現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      Special Offers[海外情報]

       

      お問合せください

      概要

      Special Offers[海外情報]

      Description
      Catalogue NumberAG252
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionGAD, control peptide for AB1511
      OverviewSynthetic peptide corresponding to amino acid residues Cys+ 572-585 of rat GAD65 (Erlander et al., 1991). The amino acid sequence is wholly conserved in rat GAD67, and the peptide is located at the C-terminus in both forms of the enzyme. Sequence: [C]DFLIEEIERLGQDL.
      Alternate Names
      • GAD
      Product Information
      PresentationWhite lyophilized powder. Soluble in water.
      Quality LevelMQ100
      Applications
      Key Applications
      • Cell Function Assay
      Application NotesAntibody blocking (AB1511)

      Optimal working dilution must be determined by the end user.
      Biological Information
      Purity>80%
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome.
      Gene Symbol
      • GAD2
      • MGC161607
      • GAD65
      • MGC161605
      • GAD-65
      • EC 4.1.1.15
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q05329 # Catalyzes the production of GABA.
      COFACTOR: Pyridoxal phosphate.
      SIZE: 585 amino acids; 65411 Da
      SUBUNIT: Homodimer (By similarity).
      SUBCELLULAR LOCATION: Cytoplasm, cytosol. Cytoplasmic vesicle. Cell junction, synapse, presynaptic cell membrane; Lipid-anchor. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
      PTM: Phosphorylated; which does not affect kinetic parameters or subcellular location. & Palmitoylated; which is required for presynaptic clustering.
      SIMILARITY: SwissProt: Q05329 ## Belongs to the group II decarboxylase family.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsLong term storage at -20°C in a sealed container with desiccant for up to 12 months after date of receipt.
      Packaging Information
      Material Size50 µg
      Global Trade Item Number
      カタログ番号 GTIN
      AG252 04053252516412