数量	カタログ番号	注文内容	Qty/Pk	価格
			96-Well Plate

数量	カタログ番号	注文内容	Qty/Pk	価格
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

343290 Sigma-AldrichFluoxetine, Hydrochloride - CAS 56296-78-7 - Calbiochem

A cell-permeable phenylpropylamine derived anti-depressant that acts as a selective serotonin re-uptake inhibitor (SSRI).

Fluoxetine, Hydrochloride - CAS 56296-78-7 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

(M)SDS
試験成績書（CoA）
参考資料
Data Sheet

同義語: dl-N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine, HCl, (±)-N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-p-tolyl)oxy]propylamine, HCl, LY-110140, Prozac

Primary Target: Selective serotonin re-uptake inhibitor

View This Product on Sigma-Aldrich

お勧めの製品

概要

Replacement Information

主要スペック表

CAS #	Empirical Formula
56296-78-7	C₁₇H₁₈F₃NO • HCL

価格＆在庫状況

カタログ番号	在庫状況	包装	Qty/Pk	価格	数量
343290-25MGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	樹脂ｱﾝﾌﾟﾙ	25 mg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました

Description
Overview	A cell-permeable phenylpropylamine derived anti-depressant that acts as a selective serotonin re-uptake inhibitor (SSRI). Reported to modulate the proliferation of T-cells by increasing the Ca²⁺ influx and thereby influencing the activities of protein kinase A (PKA) and protein kinase C (PKC). Also shown to regulate the phosphorylation of DARPP-32 (dopamine-and cAMP-regulated phosphoprotein of M_r 32,000) and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors. Shown to trigger oxidative stress-induced apoptotic cell death. Also reported to initiate signaling pathways in neuronal cells leading to activation of ERK and NF-κB.
Catalogue Number	343290
Brand Family	Calbiochem®
Synonyms	dl-N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine, HCl, (±)-N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-p-tolyl)oxy]propylamine, HCl, LY-110140, Prozac

References
References	Bartholoma, P., et al. 2002. Biochem. Pharmacol. 63, 1507. Bian, J.T., et al. 2002. Eur. J. Pharmacol. 453, 159. Zhang, A., et al. 2002. J. Med. Chem. 45, 1930. Svenningsson, P., et al. 2002. Proc. Natl. Acad. Sci. USA 99, 3182. Edgar, V.A., et al. 1999. Eur. J. Pharmacol. 372, 65.

Product Information
CAS number	56296-78-7
ATP Competitive	N
Form	Solid
Hill Formula	C₁₇H₁₈F₃NO • HCL
Chemical formula	C₁₇H₁₈F₃NO • HCL
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Selective serotonin re-uptake inhibitor
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Harmful
Storage	+2°C to +8°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
カタログ番号	GTIN
343290-25MGCN	04055977195101

Documentation

Fluoxetine, Hydrochloride - CAS 56296-78-7 - Calbiochem (M)SDS

タイトル
英語版製品安全データシート（(M)SDS）

Fluoxetine, Hydrochloride - CAS 56296-78-7 - Calbiochem 試験成績書（CoA）

タイトル	ロット番号
343290	ロット番号を入力

参考資料

参考資料の概要
Bartholoma, P., et al. 2002. Biochem. Pharmacol. 63, 1507. Bian, J.T., et al. 2002. Eur. J. Pharmacol. 453, 159. Zhang, A., et al. 2002. J. Med. Chem. 45, 1930. Svenningsson, P., et al. 2002. Proc. Natl. Acad. Sci. USA 99, 3182. Edgar, V.A., et al. 1999. Eur. J. Pharmacol. 372, 65.

データシート

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	05-July-2017 JSW
Synonyms	dl-N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine, HCl, (±)-N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-p-tolyl)oxy]propylamine, HCl, LY-110140, Prozac
Description	A cell-permeable phenylpropylamine derived anti-depressant that acts as a selective serotonin re-uptake inhibitor (SSRI). Reported to modulate the proliferation of T cells by increasing the Ca²⁺ influx thereby influencing the activities of protein kinase A (PKA) and protein kinase C (PKC). Inhibits leak K⁺ currents in a reversible and voltage-independent manner (IC₅₀ = 780 nM). Also shown to regulate the phosphorylation of DARPP-32 (dopamine-and cAMP-regulated phosphoprotein of Mr 32,000) and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors. Triggers oxidative stress-induced apoptotic cell death and initiates signaling pathways in neuronal cells leading to an activation of ERK and NF-κB.
Form	Solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	56296-78-7
Chemical formula	C₁₇H₁₈F₃NO • HCL
Structure formula
Purity	≥98% by HPLC
Solubility	H₂O (5 mg/ml) or Methanol (100 mg/ml)
Storage	Protect from light +2°C to +8°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Harmful
Merck USA index	14, 4185
References	Bartholoma, P., et al. 2002. Biochem. Pharmacol. 63, 1507. Bian, J.T., et al. 2002. Eur. J. Pharmacol. 453, 159. Zhang, A., et al. 2002. J. Med. Chem. 45, 1930. Svenningsson, P., et al. 2002. Proc. Natl. Acad. Sci. USA 99, 3182. Edgar, V.A., et al. 1999. Eur. J. Pharmacol. 372, 65.

カテゴリー

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Calcium Signaling > Other Calcium Channel Modulators

製品がカートに追加されました