Millipore Sigma Vibrant Logo

344145 FPTase, Rat, Recombinant, E. coli

FPTase, Rat, Recombinant, E. coli, a heterodimeric enzyme catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins. Recognizes the C-terminal CAAX cysteine motif.

FPTase, Rat, Recombinant, E. coli: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: Farnesyl Proteintransferase, FTase

View This Product on Sigma-Aldrich
344145
価格＆在庫状況を照会

概要

Replacement Information

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
344145-100UGCN
在庫状況検索中…
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 樹脂ｱﾝﾌﾟﾙ 100 μg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      Description
      OverviewRecombinant, rat FPTase expressed in E. coli. A heterodimeric enzyme that catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins including Ras. Recognizes the C-terminal CAAX cysteine motif where the farnesylated cysteine is followed by two aliphatic amino acids and either leucine or serine.
      M.W. α-subunit: ~48,000; β-subunit: ~46,000
      Catalogue Number344145
      Brand Family Calbiochem®
      SynonymsFarnesyl Proteintransferase, FTase
      References
      ReferencesHightower, K.E., et al. 2001. Biochem. J. 360, 625.
      Zimmerman, K.K., et al. 1998. Protein Expr. Purif. 14, 395.
      Reiss, Y., et al. 1990. Cell 62, 81.
      Product Information
      FormLiquid
      FormulationIn 25 mM HEPES, pH 7.2, 40 mM NaCl, 5 µM ZnCl₂, 1 mM TECP
      Quality LevelMQ200
      Applications
      ApplicationFPTase, Rat, Recombinant, E. coli, a heterodimeric enzyme catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins. Recognizes the C-terminal CAAX cysteine motif.
      Biological Information
      Biological activity1 pmol of FPTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
      Purity≥85% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      344145-100UGCN 04055977215229

      Documentation

      FPTase, Rat, Recombinant, E. coli (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      FPTase, Rat, Recombinant, E. coli 試験成績書（CoA）

      タイトルロット番号
      344145

      参考資料

      参考資料の概要
      Hightower, K.E., et al. 2001. Biochem. J. 360, 625.
      Zimmerman, K.K., et al. 1998. Protein Expr. Purif. 14, 395.
      Reiss, Y., et al. 1990. Cell 62, 81.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-March-2023 JSW
      SynonymsFarnesyl Proteintransferase, FTase
      DescriptionRecombinant, rat FPTase expressed in E. coli. A heterodimeric enzyme that catalyzes the transfer of a 15-carbon isoprenoid group to a C-terminal cysteine in a variety of cellular proteins, including Ras. Recognizes the CaaX motif where the farnesylated cysteine (C) is followed by two aliphatic amino acids (aa) and either leucine or serine (X). Expressed in E. coli as an untagged recombinant protein.
      FormLiquid
      FormulationIn 25 mM HEPES, pH 7.2, 40 mM NaCl, 5 µM ZnCl₂, 1 mM TECP
      Purity≥85% by SDS-PAGE
      Biological activity1 pmol of FPTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesHightower, K.E., et al. 2001. Biochem. J. 360, 625.
      Zimmerman, K.K., et al. 1998. Protein Expr. Purif. 14, 395.
      Reiss, Y., et al. 1990. Cell 62, 81.