324761 Sigma-AldrichElastase Inhibitor V - Calbiochem
お勧めの製品
概要
Replacement Information |
---|
価格&在庫状況
カタログ番号 | 在庫状況 | 包装 | Qty/Pk | 価格 | 数量 | |
---|---|---|---|---|---|---|
324761-25MGCN |
|
ガラスビン | 25 mg |
|
— |
Description | |
---|---|
Overview | A benzoxazinone compound that acts as a potent inhibitor of human leukocyte elastase (IC50 = 29.5 nM), likely by covalently modifying active site serine. Shown to inhibit elastase secretion (IC50 = 80.8 nM), but not O2•- generation, in fLMP (Cat. No. 05-22-2500)-stimulated primary human neutrophil cultures. Reported to reduce neutrophil infiltration in lung after hemorrhagic shock in rats in vivo (1 mg/kg, i.v.). |
Catalogue Number | 324761 |
Brand Family | Calbiochem® |
Synonyms | 2-(2-Bromophenyl)-5-chloro-3,1-benzoxazin-4-one |
References | |
---|---|
References | Hsieh, P.W., et al. 2010. Eur. J. Med. Chem. 45, 3111. |
Product Information | |
---|---|
Form | Off-white solid |
Hill Formula | C₁₄H₇BrClNO₂ |
Chemical formula | C₁₄H₇BrClNO₂ |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
---|
Biological Information | |
---|---|
Primary Target | Elastase |
Purity | ≥99% by HPLC |
Physicochemical Information | |
---|---|
Cell permeable | Y |
Dimensions |
---|
Materials Information |
---|
Toxicological Information |
---|
Safety Information according to GHS |
---|
Safety Information |
---|
Product Usage Statements |
---|
Packaging Information | |
---|---|
Packaged under inert gas | Packaged under inert gas |
Transport Information |
---|
Supplemental Information |
---|
Specifications |
---|
Global Trade Item Number | |
---|---|
カタログ番号 | GTIN |
324761-25MGCN | 04055977216103 |
Documentation
Elastase Inhibitor V - Calbiochem (M)SDS
タイトル |
---|
Elastase Inhibitor V - Calbiochem 試験成績書(CoA)
タイトル | ロット番号 |
---|---|
324761 |
参考資料
参考資料の概要 |
---|
Hsieh, P.W., et al. 2010. Eur. J. Med. Chem. 45, 3111. |
データシート | ||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
|