数量	カタログ番号	注文内容	Qty/Pk	価格
			96-Well Plate

数量	カタログ番号	注文内容	Qty/Pk	価格
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

574215 Sigma-AldrichD,L-Sulforaphane - CAS 4478-93-7 - Calbiochem

D,L-Sulforaphane, CAS 4478-93-7, is an anti-tumor agent that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture.

D,L-Sulforaphane - CAS 4478-93-7 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

(M)SDS
試験成績書（CoA）
参考資料
Data Sheet

同義語: 1-Isothiocyanato-4-(methylsulfinyl)butane, R,S-Sulforaphane

Primary Target: Potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture

View This Product on Sigma-Aldrich

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概要

Replacement Information

主要スペック表

CAS #	Empirical Formula
4478-93-7	C₆H₁₁NOS₂

価格＆在庫状況

カタログ番号	在庫状況	包装	Qty/Pk	価格	数量
574215-25MGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	樹脂ｱﾝﾌﾟﾙ	25 mg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました

Description
Overview	An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture. It has been shown to be an effective agent in prevention of chemically-induced mammary tumors in rats. It also inhibits the phase I cytochrome P450 isoenzymes 2E1 and IA2 which have been associated with the activation of carcinogens. The induction of phase II enzymes is mediated by mitogen-activated protein kinase (MAPK) pathway.
Catalogue Number	574215
Brand Family	Calbiochem®
Synonyms	1-Isothiocyanato-4-(methylsulfinyl)butane, R,S-Sulforaphane

References
References	Gamet-Payrastre, L., et al. 2000. Cancer Res. 60, 1426. Yu, R., et al. 2000. J. Biol. Chem. 275, 2322. Yu, R., et al. 1999. J. Biol. Chem. 274, 27545. Barcelo, S., et al. 1998. Mutat. Res. 402, 111. Maheo, K., et al. 1997. Cancer Res. 57, 3649. Zhang, Y., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3147. Zhang, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 2399.

References

Gamet-Payrastre, L., et al. 2000. Cancer Res. 60, 1426.
Yu, R., et al. 2000. J. Biol. Chem. 275, 2322.
Yu, R., et al. 1999. J. Biol. Chem. 274, 27545.
Barcelo, S., et al. 1998. Mutat. Res. 402, 111.
Maheo, K., et al. 1997. Cancer Res. 57, 3649.
Zhang, Y., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3147.
Zhang, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 2399.

Product Information
CAS number	4478-93-7
ATP Competitive	N
Form	Slight yellow liquid
Hill Formula	C₆H₁₁NOS₂
Chemical formula	C₆H₁₁NOS₂
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications
Application	D,L-Sulforaphane, CAS 4478-93-7, is an anti-tumor agent that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture.

Biological Information
Primary Target	Potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture
Purity	≥98% by UPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze DMSO stock solutions (-20°C) and ethanol stock solutions (-70°C). DMSO stock solutions are stable for up to 3 months at -20°C and ethanol stock solutions are stable for up to 3 months at -70°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
カタログ番号	GTIN
574215-25MGCN	04055977189568

Documentation

D,L-Sulforaphane - CAS 4478-93-7 - Calbiochem (M)SDS

タイトル
英語版製品安全データシート（(M)SDS）

D,L-Sulforaphane - CAS 4478-93-7 - Calbiochem 試験成績書（CoA）

タイトル	ロット番号
574215	ロット番号を入力

参考資料

参考資料の概要
Gamet-Payrastre, L., et al. 2000. Cancer Res. 60, 1426. Yu, R., et al. 2000. J. Biol. Chem. 275, 2322. Yu, R., et al. 1999. J. Biol. Chem. 274, 27545. Barcelo, S., et al. 1998. Mutat. Res. 402, 111. Maheo, K., et al. 1997. Cancer Res. 57, 3649. Zhang, Y., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3147. Zhang, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 2399.

参考資料の概要

データシート

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	26-March-2008 JSW
Synonyms	1-Isothiocyanato-4-(methylsulfinyl)butane, R,S-Sulforaphane
Description	An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture. Shown to be an effective agent in prevention of chemically-induce mammary tumors in rats. Also shown to inhibit the phase I cytochrome P450 isoenzymes 2E1 and IA2 that have been associated with the activation of carcinogens. The induction of phase II enzymes is mediated by the mitogen-activated protein kinase (MAPK) pathway.
Form	Slight yellow liquid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	4478-93-7
Chemical formula	C₆H₁₁NOS₂
Structure formula
Purity	≥98% by UPLC
Solubility	DMSO (20 mg/ml) or ethanol (10 mg/ml)
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze DMSO stock solutions (-20°C) and ethanol stock solutions (-70°C). DMSO stock solutions are stable for up to 3 months at -20°C and ethanol stock solutions are stable for up to 3 months at -70°C.
Toxicity	Standard Handling
References	Gamet-Payrastre, L., et al. 2000. Cancer Res. 60, 1426. Yu, R., et al. 2000. J. Biol. Chem. 275, 2322. Yu, R., et al. 1999. J. Biol. Chem. 274, 27545. Barcelo, S., et al. 1998. Mutat. Res. 402, 111. Maheo, K., et al. 1997. Cancer Res. 57, 3649. Zhang, Y., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3147. Zhang, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 2399.

カテゴリー

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Anticancer Agents

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