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233155 Cleland’s Reagent - CAS 3483-12-3 - Calbiochem

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233155
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
3483-12-3C₄H₁₀O₂S₂

価格&在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
233155-100GMCN
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      ガラスビン 100 gm
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      233155-10GMCN
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          樹脂アンプル 10 gm
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          233155-1KGCN
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              233155-25GMCN
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                  233155-500GMCN
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                      ガラスビン 500 gm
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                      233155-5GMCN
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                          Description
                          OverviewA protective agent for SH groups. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. Does not contain waxy surfactant found in many other preparations.
                          Oxidized dithiothreitol: ≤0.5%.
                          Catalogue Number233155
                          Brand Family Calbiochem®
                          SynonymsDithiothreitol, DTT
                          References
                          ReferencesGailis, L. 1994. Eur. J. Pharmacol. 292, 39.
                          Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
                          Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
                          Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
                          Cleland, W.W. 1964. Biochemistry 3, 480.
                          Product Information
                          CAS number3483-12-3
                          FormWhite to off-white powder
                          Hill FormulaC₄H₁₀O₂S₂
                          Chemical formulaC₄H₁₀O₂S₂
                          Quality LevelMQ100
                          Applications
                          Biological Information
                          Purity≥97% by titration
                          Physicochemical Information
                          ContaminantsHeavy metals: ≤1 ppm
                          Heavy metals<1 ppm
                          Dimensions
                          Materials Information
                          Toxicological Information
                          Safety Information according to GHS
                          RTECSEK1610000
                          Safety Information
                          R PhraseR: 22-36/38

                          Harmful if swallowed.
                          Irritating to eyes and skin.
                          S PhraseS: 36-26

                          Wear suitable protective clothing.
                          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
                          Product Usage Statements
                          Storage and Shipping Information
                          Ship Code Ambient Temperature Only
                          Toxicity Harmful
                          Storage +2°C to +8°C
                          Do not freeze Ok to freeze
                          Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
                          Packaging Information
                          Packaged under inert gas Packaged under inert gas
                          Transport Information
                          Supplemental Information
                          Specifications
                          Global Trade Item Number
                          カタログ番号 GTIN
                          233155-100GMCN 07790788054274
                          233155-10GMCN 04055977217698
                          233155-1KGCN 04055977217681
                          233155-25GMCN 04055977217711
                          233155-500GMCN 04055977217735
                          233155-5GMCN 04055977217728

                          Documentation

                          Cleland’s Reagent - CAS 3483-12-3 - Calbiochem (M)SDS

                          タイトル

                          英語版製品安全データシート((M)SDS) 

                          Cleland’s Reagent - CAS 3483-12-3 - Calbiochem 試験成績書(CoA)

                          タイトルロット番号
                          233155

                          参考資料

                          参考資料の概要
                          Gailis, L. 1994. Eur. J. Pharmacol. 292, 39.
                          Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
                          Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
                          Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
                          Cleland, W.W. 1964. Biochemistry 3, 480.

                          カタログ

                          タイトル
                          Bulk Product Guide
                          データシート

                          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                          Revision29-April-2008 RFH
                          SynonymsDithiothreitol, DTT
                          DescriptionDTT is a water-soluble protective reagent for sulfhydryl groups. It maintains monothiols in the reduced state and reduces disulfides quantitatively. Most widely used for the study of disulfide exchange reactions of protein disulfides. DTT readily permeates cell membranes. Protects protein sulfhydryls and restores enzyme activity lost by the oxidation of sulfhydryl groups in vitro. As a reducing agent, it cyclizes as it reduces disulfides to thiols, so the reaction is "driven" to completion without using large excesses of reductant. If free thiols are to be assayed later, excess reductant must be removed by dialysis or some other appropriate method. Alternatively, an immobilized form of DTT (REDUCTACRYL Reagent, Cat. No. 233157) can be used. Oxidized dithiothreitol: ≤0.5%.
                          FormWhite to off-white powder
                          Intert gas (Yes/No) Packaged under inert gas
                          CAS number3483-12-3
                          RTECSEK1610000
                          Chemical formulaC₄H₁₀O₂S₂
                          Purity≥97% by titration
                          ContaminantsHeavy metals: ≤1 ppm
                          SolubilityEthanol or H₂O (30 mg/ml)
                          Storage +2°C to +8°C
                          Do Not Freeze Ok to freeze
                          Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
                          Toxicity Harmful
                          Merck USA index14, 3376
                          ReferencesGailis, L. 1994. Eur. J. Pharmacol. 292, 39.
                          Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
                          Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
                          Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
                          Cleland, W.W. 1964. Biochemistry 3, 480.