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14-516 Cdk5/p25 Protein, active, 10 µg

Active complex of N-terminal His6-tagged, recombinant, full-length human Cdk5 & N-terminal GST-tagged, recombinant, full-length human p25, for use in Kinase Assays.

Cdk5/p25 Protein, active, 10 µg: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
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14-516
10 µg  Also available in 250 µg size --call for pricing and availability and reference catalog number 14-516M when ordering the 250 µg size.
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      概要

      Replacement Information
      Description
      Catalogue Number14-516
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionCdk5/p25 Protein, active, 10 µg
      OverviewComplex of N-terminal His6-tagged, recombinant, full-length human cdk5 and Nterminal GST-tagged, recombinant, full-length human p25
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive complex of N-terminal His6-tagged, recombinant, full-length human Cdk5 & N-terminal GST-tagged, recombinant, full-length human p25, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceCo-expressed by baculovirus in Sf21 insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • CDK5
      • PSSALRE
      Protein TargetCDK5/p25
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyCMGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q00535 # Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
      SIZE: 292 amino acids; 33304 Da
      SUBUNIT: Heterodimer of a catalytic subunit and a regulatory subunit (p35). Found in a trimolecular complex with CABLES1 and ABL1. Interacts with CABLES1 (By similarity). Interacts with AATK.
      SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell projection, lamellipodium (By similarity). Cell projection, growth cone (By similarity). Note=In axonal growth cone with extension to the peripheral lamellipodia (By similarity).
      SIMILARITY: SwissProt: Q00535 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. & Contains 1 protein kinase domain.
      Molecular Weight34.4kDa (cdk5), 49.4kDa (p25)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of Histone H1
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -70°C
      Packaging Information
      Material Size10 µg
      Material PackageAlso available in 250 µg size --call for pricing and availability and reference catalog number 14-516M when ordering the 250 µg size.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      14-516 04053252284465

      Documentation

      Cdk5/p25 Protein, active, 10 µg (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Cdk5/p25 Protein, active, 10 µg 試験成績書（CoA）

      タイトルロット番号
      CDK5/p25, active - 1575904-C 1575904-C
      CDK5/p25, active - 1575904-E 1575904-E
      CDK5/p25, active - 1575904-G 1575904-G
      CDK5/p25, active - 1575904-H 1575904-H
      CDK5/p25, active - 1575904-I 1575904-I
      CDK5/p25, active - 1575904-J 1575904-J
      CDK5/p25, active - 1575904-K 1575904-K
      CDK5/p25, active - 1575904-M 1575904-M

      関連製品＆アプリケーション

      Alternative Packsize

      カタログ番号 説明  
      14-516M Cdk5/p25 Protein, active, 250 µg 価格＆在庫状況を表示

      製品ファミリー

      Kinase & Phosphatase Products

      Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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      カテゴリー

      Life Science Research > タンパク質と酵素 > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases