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219372 Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem

Cathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).

Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
Primary Target: cathepsin G
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219372
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
429676-93-7C₃₆H₃₃N₂O₆P

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219372-1MGCN
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      Description
      OverviewA potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G [IC50 = 53 nM and Ki = 63 nM]. Weakly inhibits chymotrypsin (Ki = 1.5 µM) and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
      Catalogue Number219372
      Brand Family Calbiochem®
      References
      ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
      Product Information
      CAS number429676-93-7
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₃₆H₃₃N₂O₆P
      Chemical formulaC₃₆H₃₃N₂O₆P
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationCathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).
      Biological Information
      Primary Targetcathepsin G
      Primary Target IC<sub>50</sub>53 nM
      Primary Target K<sub>i</sub>63 nM for cathepsin G
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      219372-1MGCN 04055977202267

      Documentation

      Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem 試験成績書（CoA）

      タイトルロット番号
      219372

      参考資料

      参考資料の概要
      Greco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-April-2011 RFH
      DescriptionA potent, selective, reversible, and competitive non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM). Weakly inhibits chymotrypsin (Ki = 1.5 µM) and does not have any significant inhibitory effect on thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number429676-93-7
      Chemical formulaC₃₆H₃₃N₂O₆P
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (5 mg/ml) or Methanol
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.