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218753 Caspase-5 Inhibitor I

Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.

Caspase-5 Inhibitor I: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: Z-WE(OMe)HD(OMe)-FMK

Primary Target: caspase-1, caspase-4, caspase-5, caspase-8
View This Product on Sigma-Aldrich
218753
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概要

Replacement Information

主要スペック表

Empirical Formula
C₃₇H₄₂FN₇O₁₀

価格＆在庫状況

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218753-1MGCN
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      Description
      OverviewA potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.
      Catalogue Number218753
      Brand Family Calbiochem®
      SynonymsZ-WE(OMe)HD(OMe)-FMK
      References
      ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Rano, T., et al. 1997. Chem. Biol. 4, 149.
      Product Information
      FormWhite solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₃₇H₄₂FN₇O₁₀
      Chemical formulaC₃₇H₄₂FN₇O₁₀
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcaspase-1, caspase-4, caspase-5, caspase-8
      Puritysingle spot by TLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceZ-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      218753-1MGCN 04055977219098

      Documentation

      Caspase-5 Inhibitor I (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Caspase-5 Inhibitor I 試験成績書（CoA）

      タイトルロット番号
      218753

      参考資料

      参考資料の概要
      Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Rano, T., et al. 1997. Chem. Biol. 4, 149.

      カタログ

      タイトル
      Caspases and other Apoptosis Related Tools Brochure
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-June-2008 JSW
      SynonymsZ-WE(OMe)HD(OMe)-FMK
      DescriptionA potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4.
      FormWhite solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₃₇H₄₂FN₇O₁₀
      Peptide SequenceZ-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
      Puritysingle spot by TLC
      SolubilityDMSO (5 mg/ml)
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
      Toxicity Standard Handling
      ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Rano, T., et al. 1997. Chem. Biol. 4, 149.