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235425 Caspase-3 Substrate II, Fluorogenic - CAS 169332-61-0 - Calbiochem

Fluorogenic caspase-3 substrate.

Caspase-3 Substrate II, Fluorogenic - CAS 169332-61-0 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: Ac-DEVD-AMC

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235425
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概要

Replacement Information

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235425-1MGCN
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      		 樹脂ｱﾝﾌﾟﾙ 1 mg
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      235425-5MGCN
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          		 樹脂ｱﾝﾌﾟﾙ 5 mg
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          Description
          OverviewFluorogenic caspase-3 substrate. Cleavage of this substrate by caspase-3 shows Michaelis-Menten kinetics (Km = 9.7 ± 1.0 µM). Also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10.
          Catalogue Number235425
          Brand Family Calbiochem®
          SynonymsAc-DEVD-AMC
          References
          ReferencesHermission, M., et al. 2000. Oncogene 19, 2338.
          Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
          Nicholson, D.W., et al. 1995. Nature 376, 37.
          Product Information
          CAS number169332-61-0
          ATP CompetitiveN
          FormOff-white solid
          Hill FormulaC₃₀H₃₇N₅O₁₃
          Chemical formulaC₃₀H₃₇N₅O₁₃
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetFluorogenic caspase-3 substrate
          Primary Target IC<sub>50</sub>Km = 9.7 ± 1.0 µM for cleavage of this substrate by caspase-3
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide SequenceAc-Asp-Glu-Val-Asp-AMC
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          カタログ番号 GTIN
          235425-1MGCN 04055977217032
          235425-5MGCN 04055977217049

          Documentation

          Caspase-3 Substrate II, Fluorogenic - CAS 169332-61-0 - Calbiochem (M)SDS

          タイトル

          英語版製品安全データシート（(M)SDS） 

          Caspase-3 Substrate II, Fluorogenic - CAS 169332-61-0 - Calbiochem 試験成績書（CoA）

          タイトルロット番号
          235425

          参考資料

          参考資料の概要
          Hermission, M., et al. 2000. Oncogene 19, 2338.
          Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
          Nicholson, D.W., et al. 1995. Nature 376, 37.

          カタログ

          タイトル
          Caspases and other Apoptosis Related Tools Brochure
          データシート

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision31-March-2011 RFH
          SynonymsAc-DEVD-AMC
          DescriptionFluorogenic CPP32/Apopain substrate. Cleavage of this substrate by CPP32/Apopain shows Michaelis-Menten kinetics (Km = 9.7 ± 1.0 µM). Cleavage can be monitored by excitation at 380 nm and emission at 460 nm.
          FormOff-white solid
          CAS number169332-61-0
          Chemical formulaC₃₀H₃₇N₅O₁₃
          Peptide SequenceAc-Asp-Glu-Val-Asp-AMC
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (10 mM)
          Storage Protect from light
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesHermission, M., et al. 2000. Oncogene 19, 2338.
          Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
          Nicholson, D.W., et al. 1995. Nature 376, 37.