Millipore Sigma Vibrant Logo

400011 Caspase-1 Inhibitor I, Cell-Permeable - Calbiochem

Caspase-1 Inhibitor I, Cell-Permeable, inhibits the activity of caspase-1 (Ki = 1 nM), 4 & 5. The N-terminal corresponds to the h-region of the signal peptide of K-FGF that confers cell-permeability.

Caspase-1 Inhibitor I, Cell-Permeable - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: ICE Inhibitor I, Cell-permeable, YVAD-CHO, Cell-permeable, Ac-AAVALLPAVLLALLAPYVAD-CHO

Primary Target: Caspase-1
View This Product on Sigma-Aldrich
400011
価格＆在庫状況を照会

概要

Replacement Information

主要スペック表

Empirical Formula
C₉₇H₁₆₀N₂₀O₂₄

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
400011-1MGCN
在庫状況検索中…
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 樹脂ｱﾝﾌﾟﾙ 1 mg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      Description
      OverviewA cell-permeable inhibitor of caspase-1 (ICE; Interleukin-1β Converting Enzyme), caspase-4, and caspase-5. The C-terminal YVAD-CHO sequence of this peptide is a highly specific, potent, and reversible inhibitor of caspase-1 (Ki = 1 nM). The N-terminal sequence (amino acid residues 1-16) corresponds to the hydrophobic region (h-region) of the signal peptide of the Kaposi fibroblast growth factor (K-FGF) and confers cell-permeability to the peptide.
      Catalogue Number400011
      Brand Family Calbiochem®
      SynonymsICE Inhibitor I, Cell-permeable, YVAD-CHO, Cell-permeable, Ac-AAVALLPAVLLALLAPYVAD-CHO
      References
      ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
      Hilbi, H., et al. 1998. J. Biol. Chem. 273, 32895.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Lin, Y.-Z., et al. 1996. J. Biol. Chem. 271, 5305.
      Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.
      Reiter, L.A. 1994. Int. J. Pept. Protein Res. 43, 87.
      Thornberry, N.A., et al. 1994. Biochemistry 33, 3934.
      Thornberry, N.A., et al. 1994. Methods Enzymol. 244, 615.
      Thornberry, N.A., et al. 1992. Nature 356, 768.
      Product Information
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₉₇H₁₆₀N₂₀O₂₄
      Chemical formulaC₉₇H₁₆₀N₂₀O₂₄
      ReversibleY
      Quality LevelMQ100
      Applications
      ApplicationCaspase-1 Inhibitor I, Cell-Permeable, inhibits the activity of caspase-1 (Ki = 1 nM), 4 & 5. The N-terminal corresponds to the h-region of the signal peptide of K-FGF that confers cell-permeability.
      Biological Information
      Primary TargetCaspase-1
      Primary Target K<sub>i</sub>1 nM
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-CHO
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      400011-1MGCN 04055977212624

      Documentation

      Caspase-1 Inhibitor I, Cell-Permeable - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Caspase-1 Inhibitor I, Cell-Permeable - Calbiochem 試験成績書（CoA）

      タイトルロット番号
      400011

      参考資料

      参考資料の概要
      Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
      Hilbi, H., et al. 1998. J. Biol. Chem. 273, 32895.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Lin, Y.-Z., et al. 1996. J. Biol. Chem. 271, 5305.
      Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.
      Reiter, L.A. 1994. Int. J. Pept. Protein Res. 43, 87.
      Thornberry, N.A., et al. 1994. Biochemistry 33, 3934.
      Thornberry, N.A., et al. 1994. Methods Enzymol. 244, 615.
      Thornberry, N.A., et al. 1992. Nature 356, 768.

      カタログ

      タイトル
      Caspases and other Apoptosis Related Tools Brochure
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-July-2014 JSW
      SynonymsICE Inhibitor I, Cell-permeable, YVAD-CHO, Cell-permeable, Ac-AAVALLPAVLLALLAPYVAD-CHO
      DescriptionA cell-permeable inhibitor of caspase-1 (ICE; interleukin-1β converting enzyme). The C-terminal YVAD-CHO sequence of this peptide is a highly specific, potent, and reversible inhibitor of caspase-1 (Ki = 1 nM). The N-terminal sequence (residues 1-16) corresponds to the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF) and confers cell-permeability to the peptide.
      FormWhite solid
      Chemical formulaC₉₇H₁₆₀N₂₀O₂₄
      Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-CHO
      Purity≥97% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
      Hilbi, H., et al. 1998. J. Biol. Chem. 273, 32895.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Lin, Y.-Z., et al. 1996. J. Biol. Chem. 271, 5305.
      Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.
      Reiter, L.A. 1994. Int. J. Pept. Protein Res. 43, 87.
      Thornberry, N.A., et al. 1994. Biochemistry 33, 3934.
      Thornberry, N.A., et al. 1994. Methods Enzymol. 244, 615.
      Thornberry, N.A., et al. 1992. Nature 356, 768.