205531 Sigma-AldrichCA-074 Me - Calbiochem
CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.
More>> CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B. Less<<CA-074 Me - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
同義語: Cathepsin B Inhibitor IV, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester
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概要
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主要スペック表
| Empirical Formula |
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| C₁₉H₃₁N₃O₆ |
価格＆在庫状況
| カタログ番号 | 在庫状況 | 包装 | Qty/Pk | 価格 | 数量 | |
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| 205531-1MGCN |
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樹脂ｱﾝﾌﾟﾙ | 1 mg |
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| Description | |
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| Overview | A cell-permeable analog of CA-074 (Cat. No. 205530) that acts as an irreversible inhibitor of intracellular cathepsin B. Reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro. |
| Catalogue Number | 205531 |
| Brand Family | Calbiochem® |
| Synonyms | Cathepsin B Inhibitor IV, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester |
| Product Information | |
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| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₁₉H₃₁N₃O₆ |
| Chemical formula | C₁₉H₃₁N₃O₆ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | cathepsin B |
| Primary Target IC<sub>50</sub> | 2.24 nM against cathepsin B |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Safety Information according to GHS |
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| Specifications |
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| Global Trade Item Number | |
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| カタログ番号 | GTIN |
| 205531-1MGCN | 07790788048433 |
Documentation
CA-074 Me - Calbiochem (M)SDS
| タイトル |
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CA-074 Me - Calbiochem 試験成績書（CoA）
| タイトル | ロット番号 |
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| 205531 |
参考資料
| 参考資料の概要 |
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| Sever, N., et al. 2002. Biol. Chem. 383, 839. Authier, F., et al. 1999. J. Biol. Chem. 274, 33723. Hill, P.A., et al. 1994. J. Cell Biochem. 56, 118. Buttle, D.J., et al. 1992. Arch. Biochem. Biophys. 299, 377. |
引用
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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