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200484 Bestatin - CAS 58970-76-6 - Calbiochem

Bestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.

Bestatin - CAS 58970-76-6 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu

Primary Target: amino peptidase b
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200484
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
58970-76-6C₁₆H₂₄N₂O₄

価格＆在庫状況

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      		 樹脂ｱﾝﾌﾟﾙ 10 mg
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      Description
      OverviewBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has antitumor properties. Also available as a 50 mM solution in water (Cat. No. 200488).
      Catalogue Number200484
      Brand Family Calbiochem®
      Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
      References
      ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
      Product Information
      CAS number58970-76-6
      ATP CompetitiveN
      FormWhite crystalline solid
      Hill FormulaC₁₆H₂₄N₂O₄
      Chemical formulaC₁₆H₂₄N₂O₄
      ReversibleN
      Quality LevelMQ100
      Applications
      ApplicationBestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.
      Biological Information
      Primary Targetamino peptidase b
      Purity>99% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSOH2915000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      200484-10MGCN 04055977221459

      Documentation

      Bestatin - CAS 58970-76-6 - Calbiochem (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Bestatin - CAS 58970-76-6 - Calbiochem 試験成績書（CoA）

      タイトルロット番号
      200484

      参考資料

      参考資料の概要
      Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.

      引用

      Title
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
      		•
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-May-2013 JSW
      Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
      DescriptionBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM.
      FormWhite crystalline solid
      CAS number58970-76-6
      RTECSOH2915000
      Chemical formulaC₁₆H₂₄N₂O₄
      Purity>99% by HPLC
      SolubilityDMSO (2 mg/ml) or Methanol (5 mg/ml). Unstable in aqueous solution; dilute just prior to use.
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 9842
      ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
      Citation
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
      		•