Millipore Sigma Vibrant Logo

GF168 BMP-6 Protein, Human Recombinant

View This Product on Sigma-Aldrich
GF168
10 µg  
価格を検索中…
価格が見つかりません
Minimum Quantity needs to be mulitiple of
Maximum Quantity is
弊社照会 詳細を表示 
値引
()
 
弊社照会
現在国内在庫なし
現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

       

      お問合せください

      概要

      Replacement Information

      主要スペック表

      SourcePurity
      HEK293 CellsProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 95% pure by SDS-PAGE gel and HPLC analyses
      Description
      Catalogue NumberGF168
      DescriptionBMP-6 Protein, Human Recombinant
      Alternate Names
      • Bone Morphogenetic Protein 6
      • BMP6
      • VRR-1
      • VG-1-related protein
      Background InformationBone Morphogenetic Protein 6 (BMP-6), also known as Vgr-1, is one of at least 15 structurally and functionally related BMPs which are members of the transforming growth factor β (TGF-β) superfamily. TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines; however, its function in promoting breast cancer development is unknown. Recombinant human BMP-6 is a 26.2 kDa homodimeric glycoprotein consisting of two 117 amino acid subunits, which correspond to amino acid residues 397 to 513 of the full-length BMP-6 precursor.
      References
      Product Information
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      ApplicationThe Bone Morphogenetic Protein 6 also known as Vgr-1 protein, is one of at least 15 structurally & functionally related BMPs which are members of the TGF-β superfamily.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 95% pure by SDS-PAGE gel and HPLC analyses
      SourceHEK293 Cells
      Cross ReactivityNone
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 μg/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      GF168 04053252691256

      Documentation

      BMP-6 Protein, Human Recombinant (M)SDS

      タイトル

      英語版製品安全データシート((M)SDS) 

      BMP-6 Protein, Human Recombinant 試験成績書(CoA)

      タイトルロット番号
      Recombinant Human BMP-6 - 2382649 2382649
      Recombinant Human -2719439 2719439
      Recombinant Human -2734721 2734721
      Recombinant Human BMP-6 - 2092749 2092749
      Recombinant Human BMP-6 - 2202474 2202474
      Recombinant Human BMP-6 - 2211058 2211058
      Recombinant Human BMP-6 - 2228118 2228118
      Recombinant Human BMP-6 - 2280910 2280910
      Recombinant Human BMP-6 - 2297278 2297278
      Recombinant Human BMP-6 - 3207608 3207608

      カタログ

      タイトル
      New Products: Volume 3, 2012

      関連製品&アプリケーション

      製品ファミリー

      カテゴリー

      Life Science Research > タンパク質と酵素 > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors