Millipore Sigma Vibrant Logo

MABC307 Anti-phospho-ULK1 (Ser 467), clone 15D12.3 Antibody

View This Product on Sigma-Aldrich
MABC307
100 µg  
価格を検索中…
価格が見つかりません
Minimum Quantity needs to be mulitiple of
Maximum Quantity is
弊社照会 詳細を表示 
値引
()
 
弊社照会
現在国内在庫なし
現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      Special Offers[海外情報]

       

      お問合せください

      概要

      Replacement Information

      Special Offers[海外情報]

      主要スペック表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC307
      DescriptionAnti-phospho-ULK1 (Ser 467), clone 15D12.3 Antibody
      Alternate Names
      • Serine/threonine-protein kinase ULK1
      • Autophagy-related protein 1 homolog
      • ATG1
      • hATG1
      • Unc-51-like kinase 1
      Background InformationULK1 or autophagy-related protein 1 homolog (ATG1) is a serine/threonine protein kinase. It is a ubiquitously expressed protein that is highly abundant in the brain, skeletal muscle, and heart. It is involved in the signaling pathway of mTOR receptors leading to the regulation of autophagy in nutrient-deprived cells. mTOR may interact with ULK1 as a complex of ULK1/FIP200/Atg13. ULK1 may play an important role in neuronal development: Elimination of ULK1's enzymatic activity by targeted disruption of its kinase domain has blocked the outgrowth of neurons in the developing mouse brain, possibly by blocking the ULK1-mediated trafficking of neurotrophins.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgMλ supernatant in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-phospho-ULK1 (Ser 467) antibody, clone 15D12.3 is validated for use in western blotting for the detection of phospho-ULK1 (Ser 467).
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human phospho-ULK1 (Ser 467).
      Clone15D12.3
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgMλ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ULK1
      • KIAA0722
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~112 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A-431 serum starved cell lysate.

      Western Blotting Analysis: 0.2 µg/mL of this antibody detected phospho-ULK1 (Ser467) in 10 µg of A-431 serum starved cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      MABC307 04053252955822

      関連製品&アプリケーション

      Related Products

      カタログ番号 説明  
      ABC112 Anti-phospho-ULK1/ATG1 (Ser758) Antibody 価格&在庫状況を表示
      ABC124 Anti-phospho-ULK1 (Ser555) Antibody 価格&在庫状況を表示

      カテゴリー

      Life Science Research > Antibodies and Assays > Primary Antibodies