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Merck

07-748-AF647

Anti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor 647 Conjugate

0.5 mg/mL, from rabbit

別名:

Histone H4

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR 647
Clone:
polyclonal
Application:
ICC
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

ALEXA FLUOR 647

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

concentration

0.5 mg/mL

technique(s)

immunocytochemistry: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

monomethylation (Lys20)

Gene Information

human ... HIST2H4B(554313)

General description

Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The histones have an amino terminal tail, a globular domain, and a carboxy-terminal tail. The four core histones, H2A, H2B, H3 and H4 assemble into the octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped in a sequence-independent manner around the octamer, forming the basic subunit of chromatin, the nucleosome. Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail, H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. This product is a conjugated version of Cat. No. 07-748.
~10 kDa observed (Refer to Cat. No. 07-748)

Immunogen

Linear peptide corresponding to Histone H4 monomethylated at Lys20.

Application

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
This Anti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor 647 Conjugate is validated for use in ICC for the detection of monomethyl Histone H4 (Lys20).

Physical form

Protein A purified
Purified rabbit conjugated antibody in buffer containing PBS and 15 mg/ml BSA with 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H4 (Lys20) in HeLa cells.

Alexa Fluor is a registered trademark of Life Technologies.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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保管分類

12 - Non Combustible Liquids

wgk

WGK 2


適用法令

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07-748-AF647:

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