Millipore Sigma Vibrant Logo

OP180 Anti-Noxa Mouse mAb (114C307)

This Anti-Noxa Mouse mAb (114C307) is validated for use in Immunoblotting for the detection of Noxa.

Anti-Noxa Mouse mAb (114C307): のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
View This Product on Sigma-Aldrich
OP180
価格＆在庫状況を照会

概要

Replacement Information

主要スペック表

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
OP180-100UGCN
在庫状況検索中…
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      		 樹脂ｱﾝﾌﾟﾙ 100 μg
      価格を検索中…
      価格が見つかりません
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      弊社照会 詳細を表示　
      値引
      ()
       
      —
      弊社照会
      		 —
      Description
      OverviewRecognizes the ~11 kDa Noxa protein in RL-7 cells.
      Catalogue NumberOP180
      Brand Family Calbiochem®
      Application Data
      Detection of human Noxa by immunoblotting. Sample: Whole cell lysate from RL-7 cells. Primary antibody: Anti-Noxa Mouse mAb (114C307) (Cat. No. OP180) (2 µg/ml). Detection: chemiluminescence.
      References
      ReferencesOda, E., et al. 2000. Science 288, 1053.
      Product Information
      FormLiquid
      FormulationIn PBS, 0.05% BSA.
      Negative controlNormal mouse serum
      Positive controlRL-7 cell lysate
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1-2 µg/ml, chemiluminescence)
      Application CommentsAntibody should be titrated for optimal results in individual system.
      Biological Information
      Immunogena recombinant protein consisting of human Noxa fused to GST
      ImmunogenHuman
      Clone114C307
      HostMouse
      IsotypeIgG₁
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C;)
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      OP180-100UGCN 04055977208849

      Documentation

      Anti-Noxa Mouse mAb (114C307) (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Anti-Noxa Mouse mAb (114C307) 試験成績書（CoA）

      タイトルロット番号
      OP180

      参考資料

      参考資料の概要
      Oda, E., et al. 2000. Science 288, 1053.

      カタログ

      タイトル
      Caspases and other Apoptosis Related Tools Brochure

      引用

      Title
    • Yolanda Fernandez, et al. (2006) Chemical Blockage of the Proteasome Inhibitory Function of Bortezomib: Impact on Tumor Cell Death. Journal of Biological Chemistry 281, 1107-1118.
      		•
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-October-2007 JSW
      ApplicationImmunoblotting (1-2 µg/ml, chemiluminescence)
      Application Data
      Detection of human Noxa by immunoblotting. Sample: Whole cell lysate from RL-7 cells. Primary antibody: Anti-Noxa Mouse mAb (114C307) (Cat. No. OP180) (2 µg/ml). Detection: chemiluminescence.
      DescriptionPurified mouse monoclonal antibody. Recognizes the ~11 kDa Noxa protein.
      BackgroundNoxa, a BH3 member of the Bcl-2 family, has recently been identified in human and mouse. Expression of the Noxa gene involves direct activation of its promoter by p53. Increased expression of Noxa occurs in normal thymocytes, but does not occur in p53-deficient thymocytes. Coimmunoprecipitation data suggests that Noxa may interact with other members of the Bcl-2 family, including Bcl-XL and Mcl-1. Data has also shown that blocking the endogenous Noxa induction results in the suppression of apoptosis. Treating cells with Noxa antisense oligonucleotides blocks radiation-induced apoptosis, and this suggests that Noxa may be a mediator of p53-dependent apoptosis.
      HostMouse
      Immunogen speciesHuman
      Immunogena recombinant protein consisting of human Noxa fused to GST
      Clone114C307
      IsotypeIgG₁
      Specieshuman
      Positive controlRL-7 cell lysate
      Negative controlNormal mouse serum
      FormLiquid
      FormulationIn PBS, 0.05% BSA.
      Concentration Label Please refer to vial label for lot-specific concentration
      Preservative≤0.1% sodium azide
      CommentsAntibody should be titrated for optimal results in individual system.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C;)
      Toxicity Standard Handling
      ReferencesOda, E., et al. 2000. Science 288, 1053.
      Citation
    • Yolanda Fernandez, et al. (2006) Chemical Blockage of the Proteasome Inhibitory Function of Bortezomib: Impact on Tumor Cell Death. Journal of Biological Chemistry 281, 1107-1118.
      		•