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AB15452 Anti-MAP2 Antibody

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AB15452
500 µL  
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      概要

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      主要スペック表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MICC, IHCChAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB15452
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-MAP2 Antibody
      Alternate Names
      • Microtubule associated protein 2
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified chicken immunoglobulin. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-MAP2 Antibody detects level of MAP2 & has been published & validated for use in IC, IH.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunohistochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed tissue.

      Immunocytochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed cells.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenSynthetic peptides corresponding to different regions of the human/mouse MAP2 protein.
      HostChicken
      SpecificityMAP2 [Microtubule associated protein 2]
      Species Reactivity
      • Mouse
      Species Reactivity NoteOther species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isforms have been described.
      Gene Symbol
      • MAP2
      • MAP2B
      • MAP-2
      • MAP2C
      • DKFZp686I2148
      • MAP2A
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P11137 # The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
      SIZE: 1827 amino acids; 199539 Da
      PTM: MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
      SIMILARITY: SwissProt: P11137 ## Contains 3 Tau/MAP repeats.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
      Packaging Information
      Material Size500 µL
      Global Trade Item Number
      カタログ番号 GTIN
      AB15452 04053252405099