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MAB2075Z Anti-Integrin β6 Antibody, clone R6G9, azide free

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MAB2075Z
100 µg  
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      概要

      Replacement Information

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      主要スペック表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, IPMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB2075Z
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Integrin β6 Antibody, clone R6G9, azide free
      Alternate Names
      • MAB2075
      References
      Product Information
      FormatPurified
      PresentationSterile-filtered liquid at 1 mg/mL in PBS, containing no preservatives.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Integrin β6 Antibody, clone R6G9, azide free is an antibody against Integrin β6 for use in FC & IP.
      Key Applications
      • Flow Cytometry
      • Immunoprecipitation
      Applications Not Recommended
      • Western Blotting
      • Inhibits Activity/Function
      Application NotesFlow cytometry

      Immunoprecipitation: Effective; however because this antibody is an IgG2a, protein G or rabbit anti-mouse IgG is helpful for capture.

      Immunohistochemistry/immunocytochemistry: The antibody recognizes alphaVbeta6 by immunohistochemistry and immunocytochemistry (acetone fix), but nuclear background staining limits usefulness in these techniques.


      Then antibody is not function blocking and not effective for western blot.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenMurine NIH 3T3 cells stably transfected with the human (6 subunit
      CloneR6G9
      HostMouse
      SpecificityMonoclonal antibody MAB2075Z, raised by immunizing Balb/c mice with murine NIH 3T3 cells stably transfected with the human beta6 subunit, recognizes the human beta6 subunit by flow cytometry and is an excellent antibody for immunoprecipitation.
      IsotypeIgG2a
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ITGB6
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P18564 # Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands.
      SIZE: 788 amino acids; 85936 Da
      SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-6 associates with alpha-V. Interacts with FLNB.
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      SIMILARITY: SwissProt: P18564 ## Belongs to the integrin beta chain family. & Contains 1 VWFA domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain frozen at -20°C in undiluted aliquots for up to 12 months.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      MAB2075Z 04053252579301

      Documentation

      Anti-Integrin β6 Antibody, clone R6G9, azide free (M)SDS

      タイトル

      英語版製品安全データシート((M)SDS) 

      Anti-Integrin β6 Antibody, clone R6G9, azide free 試験成績書(CoA)

      タイトルロット番号
      MOUSE ANTI-INTEGRIN B6 MONOCLONAL ANTIBODY 2922257
      MOUSE ANTI-INTEGRIN β6 - 3213938 3213938
      MOUSE ANTI-INTEGRIN β6 - 4008320 4008320
      MOUSE ANTI-INTEGRIN β6 MONOCLONAL ANTIBODY 3016671
      MOUSE ANTI-INTEGRIN β6 MONOCLONAL ANTIBODY 3084142
      MOUSE ANTI-INTEGRIN β6 MONOCLONAL ANTIBODY - 2432494 2432494
      MOUSE ANTI-INTEGRIN β6 MONOCLONAL ANTIBODY -2611053 2611053

      参考資料

      参考資料の概要Pub Med ID
      Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor.
      Weinacker, A, et al.
      J. Biol. Chem., 269: 6940-8 (1994)  1994

      概要を表示する
      8120056 8120056

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      カテゴリー

      Life Science Research > Antibodies and Assays > Primary Antibodies