Millipore Sigma Vibrant Logo

MAB4065 Anti-H-CAM Antibody, Pan, clone SFF-2

This Anti-H-CAM Antibody, Pan, clone SFF-2 is validated for use in FC, IC, IH, IH(P) for the detection of H-CAM.

Anti-H-CAM Antibody, Pan, clone SFF-2: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: CD44, LHR, HUTCH-I, CDW44, CDw44, ECMR-III, Epican, MGC10468, CD44R, PGP-1, MDU2, CSPG8, Pgp1, IN, MUTCH-I, MIC4, MDU3, MC56, HCELL UniProt Number: P16070
View This Product on Sigma-Aldrich
MAB4065
100 µg  
価格を検索中…
価格が見つかりません
Minimum Quantity needs to be mulitiple of
Maximum Quantity is
弊社照会 詳細を表示　
値引
()
 
—
弊社照会
—
現在国内在庫なし 現在国内在庫なし
現在国内在庫有り 
販売中止
在庫僅少
現在国内在庫あり
    Remaining : Will advise
      Remaining : Will advise
      注文対象外
      お問合せください
      Contact Customer Service

      Special Offers［海外情報］

       

      お問合せください

      概要

      Replacement Information

      Special Offers［海外情報］

      100% Performance Guaranteed

      主要スペック表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, ICC, IHC, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB4065
      Replaces04-1123
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-H-CAM Antibody, Pan, clone SFF-2
      Alternate Names
      • CD44
      • CD44std
      • CD44H
      • HCAM
      References
      Product Information
      FormatPurified
      Control
      • POSITIVE CONTROL: Lymph node (lymphocytes), skin (keratinocytes), or tonsil.
      PresentationLiquid in PBS.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-H-CAM Antibody, Pan, clone SFF-2 is validated for use in FC, IC, IH, IH(P) for the detection of H-CAM.
      Key Applications
      • Flow Cytometry
      • Immunocytochemistry
      • Immunohistochemistry
      • Immunohistochemistry (Paraffin)
      Applications Not Recommended
      • Western Blotting
      Application NotesImmunohistochemistry: 1 µg/mL; acetone fixed cryostat sections; 2 µg/mL following heat-induced epitope retrieval in 0.01 M citrate buffer, pH 6.0 (Banfalvi, 1999).
      Immunofluorescence
      Flow Cytometry: 1:20 as determined on U937 cells
      Optimal working dilutions must be determined by end user.
      Biological Information
      EpitopePan
      CloneSFF-2
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificitySpecific for human standard CD44. Does not distinguish between splice variants (exons v3v10).
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
      Gene Symbol
      • CD44
      • LHR
      • HUTCH-I
      • CDW44
      • CDw44
      • ECMR-III
      • Epican
      • MGC10468
      • CD44R
      • PGP-1
      • MDU2
      • CSPG8
      • Pgp1
      • IN
      • MUTCH-I
      • MIC4
      • MDU3
      • MC56
      • HCELL
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P16070 # Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
      SIZE: 742 amino acids; 81554 Da
      SUBUNIT: Interacts with HA, as well as other glycosaminoglycans, collagen, laminin, and fibronectin via its N-terminal segment. Interacts with ANK, the ERM proteins (VIL2, RDX and MSN), and NF2 via its C-terminal segment.
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      TISSUE SPECIFICITY: An epithelial isoform (CD44E) is expressed by cells of epithelium and highly expressed by carcinomas. An hematopoietic isoform (CD44H) is expressed by cells of mesodermal origin. Expression is repressed in neuroblastoma cells.
      PTM: Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors. & N-glycosylated. & O-glycosylated; contains more-or-less-sulfated chondroitin sulfate glycans, whose number may affect the accessibility of specific proteinases to their cleavage site(s). & Phosphorylated; activation of PKC results in the dephosphorylation of Ser-706 (constitutive phosphorylation site), and the phosphorylation of Ser-672.
      SIMILARITY: SwissProt: P16070 ## Contains 1 Link domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsPrior to opening maintain at -20°C until expiration date. After opening maintain frozen at -20°C in undiluted aliquots until expiration date. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      MAB4065 04053252399428

      Documentation

      Anti-H-CAM Antibody, Pan, clone SFF-2 (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      Anti-H-CAM Antibody, Pan, clone SFF-2 試験成績書（CoA）

      タイトルロット番号
      MOUSE ANTI-PAN CD44 [H-CAM] 2472892
      MOUSE ANTI-PAN CD44 [H-CAM] - 3159366 3159366
      MOUSE ANTI-PAN CD44 [H-CAM] - 3910180 3910180
      MOUSE ANTI-PAN CD44 [H-CAM] -2701619 2701619
      MOUSE ANTI-PAN CD44 [H-CAM] -2707220 2707220
      MOUSE ANTI-PAN CD44 [H-CAM] MONOCLONAL ANTIBODY -
      MOUSE ANTI-PAN CD44 [H-CAM] MONOCLONAL ANTIBODY - 2117135 2117135
      MOUSE ANTI-PAN CD44 [H-CAM] MONOCLONAL ANTIBODY - 2292287 2292287
      MOUSE ANTI-PAN CD44 [H-CAM] MONOCLONAL ANTIBODY - 4041245 4041245
      MOUSE ANTI-PAN CD44 [H-CAM] MONOCLONAL ANTIBODY -2535276 2535276

      参考資料

      参考資料の概要Pub Med ID
      Intravenous administration of human mesenchymal stem cells after noise- or drug-induced hearing loss in rats.
      Byung Yoon Choi,Jae-Jin Song,Sun O Chang,Seung Up Kim,Seung Ha Oh
      Acta oto-laryngologica  132 Suppl 1  2012

      概要を表示する       		22582790 22582790

      カタログ

      タイトル
      Human Stem Cell Systems

      関連製品＆アプリケーション

      Related Products

      カタログ番号 説明  
      AB2080 Anti-CD44v6 Antibody, exon v6 価格＆在庫状況を表示
      AB2081 Anti-CD44v3 Antibody, exon v3 価格＆在庫状況を表示
      AB2082 Anti-CD44v10 Antibody, exon v10 価格＆在庫状況を表示
      AB2083 Anti-CD44v7 Antibody, exon v7 価格＆在庫状況を表示
      CBL154 Anti-H-CAM Antibody, clone F10-44-2 価格＆在庫状況を表示
      MAB2137 Anti-Homing Receptor Antibody, clone A020 価格＆在庫状況を表示
      MAB4073 Anti-CD44v6 Antibody, exon v6, clone VFF-18 価格＆在庫状況を表示

      カテゴリー

      Life Science Research > Antibodies and Assays > Primary Antibodies