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GR13 Anti-EGFR (Ab-3) Mouse mAb (225)

Anti-EGFR (Ab-3), mouse monoclonal, clone 225 recognizes the ~170 kDa epidermal growth factor receptor protein. It is validated for use in immunoprecipitation.

Anti-EGFR (Ab-3) Mouse mAb (225): のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: Anti- Epidermal Growth Factor Receptor

GR13
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概要

主要スペック表

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

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カタログ番号 在庫状況包装 Qty/Pk 価格 数量
GR13-100UGCN
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      		 樹脂ｱﾝﾌﾟﾙ 100 μg
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      Description
      OverviewRecognizes the ~170 kDa epidermal growth factor receptor protein. For neutralization studies Cat. No. GR13L is recommended.
      Catalogue NumberGR13
      Brand Family Calbiochem®
      SynonymsAnti- Epidermal Growth Factor Receptor
      References
      ReferencesHunter T. 1984. Nature 311, 414.
      Reynolds, F.H., et. al 1981. Nature 292, 259.
      Ushiro, H. and Cohen, S. 1980. J. Biol. Chem. 255, 8363.
      Product Information
      FormLiquid
      FormulationIn 0.05 M sodium phosphate buffer, 0.2% gelatin.
      Negative controlHL-60 cells
      Positive controlA-431 cells
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Application ReferencesOriginal Clone Kawamoto, T., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 1337. Neutralization Studies Gill, G., et al. 1984. J. Biol. Chem. 259, 7755. Kawamoto, T., et al. 1984. J. Biol. Chem. 259, 7761. Masui, H., et al. 1984. Cancer Res. 44, 1002. Kawamoto, T., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 1337. Sato, J.D., et al. 1983. Biol. Med. 1, 511.
      Key Applications Immunoprecipitation
      Application NotesImmunoprecipitation (1-2 µg per sample)
      Neutralization Studies (2 µg/ml, see application references; use Cat. No. GR13L)
      Application CommentsShown to inhibit human tumor xenographs in nude mice. It inhibits EGF binding to its receptor and is an antagonist of in vivo EGF-stimulated tyrosine kinase activity. It also inhibits A431 tumor formation in nude mice. For neutralization studies GR13L is recommended. Antibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogenpartially purified, human EGFR from A431 cells
      ImmunogenHuman
      Clone225
      HostMouse
      IsotypeIgG₁
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Yes
      Global Trade Item Number
      カタログ番号 GTIN
      GR13-100UGCN 04055977228243