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ABF187 Anti-CD79b Antibody

ABF187
100 µL  
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      概要

      Replacement Information

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      主要スペック表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IPRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABF187
      DescriptionAnti-CD79b Antibody
      Alternate Names
      • B-cell antigen receptor complex-associated protein beta chain
      • B-cell-specific glycoprotein B29
      • Ig-beta
      • Immunoglobulin-associated B29 protein
      • CD79b
      Background InformationThe B-cell antigen receptor (BCR) is a multimeric complex consisting of an antigen-recognition structure and a membrane-bound immunoglobulin (mIg), associated non-covalently with a heterodimer of Ig-alpha (encoded by the CD79A gene) and Ig-beta (encoded by the CD79B gene). Signalling through the BCR is mediated by Ig-alpha and Ig-beta cytoplsmic domain.
      References
      Product Information
      FormatSerum
      PresentationRabbit polyclonal serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-CD79b Antibody is an antibody against CD79b for use in Western Blotting, Immunoprecipitation.
      Key Applications
      • Western Blotting
      • Immunoprecipitation
      Application NotesWestern Blotting Analysis: A representative lot detected CD79b in Ramos cell lysate (Brouns, G.S., et al. (1995). International Immunology. 7(3):359-368).
      Western Blotting Analysis: A representative lot detected CD79b in Ramos and NALM-6 cell lysate (Brouns, G.S., et al. (1996). J. Biol. Chem. 271(32):19272-19278).
      Immunoprecipitation Analysis: A representative lot immunoprecipitated CD79b in Ramos cell lysate (Brouns, G.S., et al. (1995). International Immunology. 7(3):359-368).
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the cytoplasmic domain of human CD79b.
      Epitopecytoplasmic domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CD79B
      • B29
      • IGB
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight34/30/27 kDa observed. Observed range is due to multiple glycosylation sites and mature vs immature forms. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Daudi cell lysate.

      Western Blotting Analysis: A 1:2,000 dilution of this antibody detected CD79b in 10 µg of Daudi cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      ABF187 04055977163988

      Documentation

      Anti-CD79b Antibody 試験成績書(CoA)

      タイトルロット番号
      Anti-CD79b -Q2564172 Q2564172

      参考資料

      参考資料の概要Pub Med ID
      Assembled pre-B cell receptor complexes are retained in the endoplasmic reticulum by a mechanism that is not selective for the pseudo-light chain.
      Brouns, GS; de Vries, E; Neefjes, JJ; Borst, J
      The Journal of biological chemistry  271  19272-8  1996

      概要を表示する
      8702609 8702609
      Assembly and intracellular transport of the human B cell antigen receptor complex.
      Brouns, GS; de Vries, E; Borst, J
      International immunology  7  359-68  1995

      概要を表示する
      7794818 7794818

      カタログ

      タイトル
      NPI Flyer- Epigenetics and Nuclear Function Feature

      技術情報

      タイトル
      White Paper: Further considerations of antibody validation and usage.

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      カテゴリー

      Life Science Research > Antibodies and Assays > Primary Antibodies