数量	カタログ番号	注文内容	Qty/Pk	価格
			96-Well Plate

数量	カタログ番号	注文内容	Qty/Pk	価格
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

124012 Sigma-AldrichAkt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem

Akt Inhibitor V, Triciribine, CAS 35943-35-2, is a cell-permeable, selective, reversible inhibitor of the cellular phosphorylation/activation of Akt1/2/3.

Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

(M)SDS
試験成績書（CoA）
参考資料
カタログ
Data Sheet

同義語: NSC 154020, TCN, Akt/PKB Signaling Inhibitor-2, API-2

Primary Target: Akt1, Akt 2, Akt3

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概要

Replacement Information

主要スペック表

CAS #	Empirical Formula
35943-35-2	C₁₃H₁₆N₆O₄

価格＆在庫状況

カタログ番号	在庫状況	包装	Qty/Pk	価格	数量
124012-10MGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	ｶﾞﾗｽﾋﾞﾝ	10 mg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました
124012-1MGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	樹脂ｱﾝﾌﾟﾙ	1 mg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました

Description
Overview	A cell-permeable and reversible tricyclic nucleoside that selectively inhibits the cellular phosphorylation/activation of Akt1/2/3. It does not inhibit known upstream activators of Akt, i.e. PI3K or PDK. Exhibits little effect towards cellular signaling pathways mediated by PKC, PKA, SGK, Stat3, p38, ERK1/2, or JNK. Shown to preferentially induce apoptosis and growth arrest in cancer cells with aberrant Akt activity both in vitro (≥ 60% in cell proliferation at 20 µM) and in vivo (≥ 80% inhibition in tumor growth in mice at 1 mg/kg/day, i.p.). Also available in InSolution™ format (Cat. No. 124038).
Catalogue Number	124012
Brand Family	Calbiochem®
Synonyms	NSC 154020, TCN, Akt/PKB Signaling Inhibitor-2, API-2

References
References	Karst, A., et al. 2006. Cancer Res. 66, 9225. Yang, L., et al. 2004. Cancer Res. 64, 4394.

Product Information
CAS number	35943-35-2
ATP Competitive	N
Form	Solid
Hill Formula	C₁₃H₁₆N₆O₄
Chemical formula	C₁₃H₁₆N₆O₄
Reversible	Y
Structure formula Image
Quality Level	MQ100

Applications
Application	Akt Inhibitor V, Triciribine, CAS 35943-35-2, is a cell-permeable, selective, reversible inhibitor of the cellular phosphorylation/activation of Akt1/2/3.

Biological Information
Primary Target	Akt1, Akt 2, Akt3
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	RY8455000

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity	Carcinogenic / Teratogenic
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
カタログ番号	GTIN
124012-10MGCN	04055977205640
124012-1MGCN	04055977205633

Documentation

Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem (M)SDS

タイトル
英語版製品安全データシート（(M)SDS）

Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem 試験成績書（CoA）

タイトル	ロット番号
124012	ロット番号を入力

参考資料

参考資料の概要
Karst, A., et al. 2006. Cancer Res. 66, 9225. Yang, L., et al. 2004. Cancer Res. 64, 4394.

カタログ

タイトル
Akt
Biologics 31.1

データシート

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	16-January-2012 RFH
Synonyms	NSC 154020, TCN, Akt/PKB Signaling Inhibitor-2, API-2
Description	A cell-permeable and reversible tricyclic nucleoside that selectively inhibits the cellular phosphorylation/activation of Akt1/2/3 by targeting an Akt effector molecule other than PI 3-K or PDK. Exhibits little effect towards cellular signaling pathways mediated by PKC, PKA, SGK, Stat3, p38, ERK1/2, or JNK. Shown to preferentially induce apoptosis and growth arrest in cancer cells with aberrant Akt activity both in vitro (≥60% in cell proliferation at 20 µM) and in vivo (≥80% inhibition in tumor growth in mice at 1 mg/kg/day, i.p.). Also available in InSolution™ format (Cat. No. 124038.
Form	Solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	35943-35-2
RTECS	RY8455000
Chemical formula	C₁₃H₁₆N₆O₄
Structure formula
Purity	≥95% by HPLC
Solubility	DMSO (10 mg/ml). Further dilute at aqueous buffer in low micromolar concentrations.
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Carcinogenic / Teratogenic
References	Karst, A., et al. 2006. Cancer Res. 66, 9225. Yang, L., et al. 2004. Cancer Res. 64, 4394.

カテゴリー

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Akt (Protein Kinase B) Inhibitors

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