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28745 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem

This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: Dibutyryl-cAMP, Na

Primary Target: PKA
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28745
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概要

Replacement Information

主要スペック表

CAS #Empirical Formula
16980-89-5C₁₈H₂₃N₅O₈P · Na

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
28745-100MGCN
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      		 樹脂ｱﾝﾌﾟﾙ 100 mg
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      28745-25MGCN
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          		 樹脂ｱﾝﾌﾟﾙ 25 mg
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          Description
          OverviewA cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Causes an increase in the steady state level of parathyroid hormone-related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.
          Catalogue Number28745
          Brand Family Calbiochem®
          SynonymsDibutyryl-cAMP, Na
          References
          ReferencesNoveen, A., et al. 1996. Biochem. Biophys. Res. Commun. 219, 180.
          Tsai, C.H., et al. 1995. J. Cell. Physiol. 164, 108.
          Leszczynski, D., et al. 1994. Am. J. Pathol. 145, 1265.
          Miller, C., et al. 1994. J. Neurosci. Res. 38, 56.
          Hinko, A., and Soloff, M.S. 1993. Endocrinology 132, 126.
          Ikeda, K., et al. 1993. J. Biol. Chem. 268, 1174.
          Park, E.A., et al. 1993. J. Biol. Chem. 268, 613.
          Hei, Y-J., et al. 1991. Mol. Pharmacol. 39, 233.
          Posternak, T., and Weimann, G. 1974. Methods Enzymol. 38, 399.
          Product Information
          CAS number16980-89-5
          ATP CompetitiveN
          FormWhite lyophilized solid
          Hill FormulaC₁₈H₂₃N₅O₈P · Na
          Chemical formulaC₁₈H₂₃N₅O₈P · Na
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ200
          Applications
          Biological Information
          Primary TargetPKA
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSES5055500
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Aqueous stock solutions are stable for up to 3 days at 4°C or for up to 3 months at -20°C. Avoid pH >8.5.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          カタログ番号 GTIN
          28745-100MGCN 04055977197839
          28745-25MGCN 04055977090970

          Documentation

          Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem (M)SDS

          タイトル

          英語版製品安全データシート（(M)SDS） 

          Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem 試験成績書（CoA）

          タイトルロット番号
          28745

          参考資料

          参考資料の概要
          Noveen, A., et al. 1996. Biochem. Biophys. Res. Commun. 219, 180.
          Tsai, C.H., et al. 1995. J. Cell. Physiol. 164, 108.
          Leszczynski, D., et al. 1994. Am. J. Pathol. 145, 1265.
          Miller, C., et al. 1994. J. Neurosci. Res. 38, 56.
          Hinko, A., and Soloff, M.S. 1993. Endocrinology 132, 126.
          Ikeda, K., et al. 1993. J. Biol. Chem. 268, 1174.
          Park, E.A., et al. 1993. J. Biol. Chem. 268, 613.
          Hei, Y-J., et al. 1991. Mol. Pharmacol. 39, 233.
          Posternak, T., and Weimann, G. 1974. Methods Enzymol. 38, 399.
          データシート

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision11-March-2008 JSW
          SynonymsDibutyryl-cAMP, Na
          DescriptionCell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Known to cause an increase in the steady state level of the parathyroid hormone related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.
          FormWhite lyophilized solid
          CAS number16980-89-5
          RTECSES5055500
          Chemical formulaC₁₈H₂₃N₅O₈P · Na
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityH₂O (1 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Aqueous stock solutions are stable for up to 3 days at 4°C or for up to 3 months at -20°C. Avoid pH >8.5.
          Toxicity Standard Handling
          ReferencesNoveen, A., et al. 1996. Biochem. Biophys. Res. Commun. 219, 180.
          Tsai, C.H., et al. 1995. J. Cell. Physiol. 164, 108.
          Leszczynski, D., et al. 1994. Am. J. Pathol. 145, 1265.
          Miller, C., et al. 1994. J. Neurosci. Res. 38, 56.
          Hinko, A., and Soloff, M.S. 1993. Endocrinology 132, 126.
          Ikeda, K., et al. 1993. J. Biol. Chem. 268, 1174.
          Park, E.A., et al. 1993. J. Biol. Chem. 268, 613.
          Hei, Y-J., et al. 1991. Mol. Pharmacol. 39, 233.
          Posternak, T., and Weimann, G. 1974. Methods Enzymol. 38, 399.