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407294 αA-Interferon, Human, Recombinant, E. coli

αA-Interferon, Human, Recombinant, E. coli: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

同義語: rhIFN-αA

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407294
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概要

Replacement Information

価格＆在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
407294-5MUCN
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      		 樹脂ｱﾝﾌﾟﾙ 5 mu
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      Description
      OverviewRecombinant, human αA-interferon expressed in E. coli. Antiviral, anti-neoplastic agent. αA-Interferon exhibits therapeutic potential with chronic viral hepatitis, polycythemia vera, and various malignancies. It enhances natural killer cell activity, suppresses bone marrow function, and induces apoptotic cell death in non-melanoma skin cancer. NOTE: 1MU = 1,000,000 units.
      Note: 1 MU = 1,000,000 units.
      Catalogue Number407294
      Brand Family Calbiochem®
      SynonymsrhIFN-αA
      References
      ReferencesFujishima, H., et al. 1998. Int. J. Cancer 76, 423.
      Haria, M., and Benfield, P. 1995. Drugs 50, 873.
      Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
      Product Information
      Activity≥5 x 10⁶ units/ml
      Unit of DefinitionOne unit of interferon per ml of medium will cause a 50% inhibition of VSV-induced cytopathic effect on bovine MDBK cells. Units are determined with respect to the NIH international reference standard for human αA-IFN. Dilute in aqueous buffer containing at least 0.1% BSA or HSA.
      FormLiquid
      FormulationIn PBS containing 0.1% BSA.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Specific Activity≥2.8 x 10⁸ units/mg protein
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      407294-5MUCN 04055977188202

      Documentation

      αA-Interferon, Human, Recombinant, E. coli (M)SDS

      タイトル

      英語版製品安全データシート（(M)SDS） 

      αA-Interferon, Human, Recombinant, E. coli 試験成績書（CoA）

      タイトルロット番号
      407294

      参考資料

      参考資料の概要
      Fujishima, H., et al. 1998. Int. J. Cancer 76, 423.
      Haria, M., and Benfield, P. 1995. Drugs 50, 873.
      Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.

      引用

      Title
    • Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
    • Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.
      		•
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-May-2008 RFH
      SynonymsrhIFN-αA
      DescriptionRecombinant, human αA-interferon expressed in E. coli. Antiviral, anti-neoplastic agent. αA-Interferon exhibits therapeutic potential in chronic viral hepatitis, polycythemia vera, and various malignancies. It enhances natural killer cell activity, suppresses bone marrow function, and induces apoptotic cell death in non-melanoma skin cancer.
      FormLiquid
      FormulationIn PBS containing 0.1% BSA.
      Purity≥95% by SDS-PAGE
      Specific activity≥2.8 x 10⁸ units/mg protein
      Activity≥5 x 10⁶ units/ml
      Unit definitionOne unit of interferon per ml of medium will cause a 50% inhibition of VSV-induced cytopathic effect on bovine MDBK cells. Units are determined with respect to the NIH international reference standard for human αA-IFN. Dilute in aqueous buffer containing at least 0.1% BSA or HSA.
      SolubilityDilute only in buffers containing protein such as 0.1% BSA.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      Merck USA index14, 4990
      ReferencesFujishima, H., et al. 1998. Int. J. Cancer 76, 423.
      Haria, M., and Benfield, P. 1995. Drugs 50, 873.
      Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
      Citation
    • Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
    • Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.
      		•

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      カテゴリー

      Life Science Research > タンパク質と酵素 > Other Proteins