数量	カタログ番号	注文内容	Qty/Pk	価格
			96-Well Plate

数量	カタログ番号	注文内容	Qty/Pk	価格
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

149101 Sigma-Aldrich1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem

1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8, is an agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex.

1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem: のSDS（安全データシート）、CoA（試験成績書）およびCoQ（品質証明書）、カタログなど製品関連の技術資料を入手いただけます。

(M)SDS
試験成績書（CoA）
参考資料
カタログ
Data Sheet

同義語: ACPC

Primary Target: Glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex

View This Product on Sigma-Aldrich

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概要

Replacement Information

主要スペック表

CAS #	Empirical Formula
22059-21-8	C₄H₇NO₂

価格＆在庫状況

カタログ番号	在庫状況	包装	Qty/Pk	価格	数量
149101-1GMCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	ｶﾞﾗｽﾋﾞﾝ	1 gm	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました
149101-250MGCN	在庫状況検索中… — 現在国内在庫なし現在国内在庫有り販売中止在庫僅少現在国内在庫あり在庫を照会するにはログインしてください現在国内在庫有り現在国内在庫なし現在国内在庫有り Remaining : Will advise Remaining : Will advise 注文対象外お問合せください Contact Customer Service お問合せくださいお問合せください	ｶﾞﾗｽﾋﾞﾝ	250 mg	価格を検索中… 価格が見つかりません Minimum Quantity needs to be mulitiple of Maximum Quantity is 弊社照会詳細を表示　値引 () — 弊社照会納入価格を閲覧するにはログインしてください	在庫状況を照会 —	お気に入り/ショッピングリストに追加お気に入り/ショッピングリストに追加お気に入りに追加されました

Description
Overview	An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. Mimics the effects of glycine on the NMDA receptor ion channel and blocks ³H-glycine binding to rat forebrain membrane (IC₅₀ = 38 nM). Blocks NMDA-induced release of arachidonic acid (IC₅₀ = 131 µM) in cerebellar granule cells. Reduces NMDA-induced cell death in hippocampal neurons.
Catalogue Number	149101
Brand Family	Calbiochem®
Synonyms	ACPC

References
References	Viu, E., et al. 1998. J. Pharm. Exp. Ther. 285, 527. Zapata, A., et al. 1996. NeuroReport 7, 397. Kolesnikov, Y.A., et al. 1994. Life Sci. 55, 1393. Rottmann, W.H., et al. 1991. J. Mol. Biol. 222, 937. Marvizon, J.C., et al. 1989. J. Neurochem. 52, 992. Nadler, V., et al. 1988. Eur. J. Pharmacol. 157, 115. Adams, D.O., and Yang, S.F. 1979. Proc. Natl. Acad. Sci. USA 76, 170.

References

Viu, E., et al. 1998. J. Pharm. Exp. Ther. 285, 527.
Zapata, A., et al. 1996. NeuroReport 7, 397.
Kolesnikov, Y.A., et al. 1994. Life Sci. 55, 1393.
Rottmann, W.H., et al. 1991. J. Mol. Biol. 222, 937.
Marvizon, J.C., et al. 1989. J. Neurochem. 52, 992.
Nadler, V., et al. 1988. Eur. J. Pharmacol. 157, 115.
Adams, D.O., and Yang, S.F. 1979. Proc. Natl. Acad. Sci. USA 76, 170.

Product Information
CAS number	22059-21-8
ATP Competitive	N
Form	Crystalline solid
Hill Formula	C₄H₇NO₂
Chemical formula	C₄H₇NO₂
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications
Application	1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8, is an agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex.

Biological Information
Primary Target	Glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex
Primary Target IC<sub>50</sub>	38 nM in blocking 3H-glycine binding to rat forebrain membrane; 131 µM in blocking NMDA-induced release of arachidonic acid; 131 µM in cerebellar granule cells
Purity	≥ 98% by TLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	GZ1110000

Safety Information
R Phrase	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	+15°C to +30°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
カタログ番号	GTIN
149101-1GMCN	07790788059590
149101-250MGCN	04055977207521

Documentation

1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem (M)SDS

タイトル
英語版製品安全データシート（(M)SDS）

1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem 試験成績書（CoA）

タイトル	ロット番号
149101	ロット番号を入力

参考資料

参考資料の概要
Viu, E., et al. 1998. J. Pharm. Exp. Ther. 285, 527. Zapata, A., et al. 1996. NeuroReport 7, 397. Kolesnikov, Y.A., et al. 1994. Life Sci. 55, 1393. Rottmann, W.H., et al. 1991. J. Mol. Biol. 222, 937. Marvizon, J.C., et al. 1989. J. Neurochem. 52, 992. Nadler, V., et al. 1988. Eur. J. Pharmacol. 157, 115. Adams, D.O., and Yang, S.F. 1979. Proc. Natl. Acad. Sci. USA 76, 170.

参考資料の概要

カタログ

タイトル
Excitotoxic Glutamate Analogs Technical Bulletin
Pathways and Biomarkers of Glutamatergic Synapse Flyer

データシート

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	10-April-2008 RFH
Synonyms	ACPC
Description	A potent and selective ligand for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. Blocks ³H-glycine binding to rat forebrain membranes (IC₅₀ = 38 nM).
Form	Crystalline solid
CAS number	22059-21-8
RTECS	GZ1110000
Chemical formula	C₄H₇NO₂
Structure formula
Purity	≥ 98% by TLC
Solubility	H₂O (40 mg/ml). May require heating and sonication to achieve complete solubilization.
Storage	+15°C to +30°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity	Irritant
References	Viu, E., et al. 1998. J. Pharm. Exp. Ther. 285, 527. Zapata, A., et al. 1996. NeuroReport 7, 397. Kolesnikov, Y.A., et al. 1994. Life Sci. 55, 1393. Rottmann, W.H., et al. 1991. J. Mol. Biol. 222, 937. Marvizon, J.C., et al. 1989. J. Neurochem. 52, 992. Nadler, V., et al. 1988. Eur. J. Pharmacol. 157, 115. Adams, D.O., and Yang, S.F. 1979. Proc. Natl. Acad. Sci. USA 76, 170.

カテゴリー

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Neurochemicals > Agonists > Glutamate Receptor Agonists

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