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407293 α-Interferon, Mouse, Recombinant, E. coli

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407293
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概要

Replacement Information

価格&在庫状況

カタログ番号 在庫状況包装 Qty/Pk 価格 数量
407293-100KU
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      樹脂アンプル 100 ku
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      Description
      OverviewRecombinant, mouse α-interferon expressed in E. coli. Antiviral and anti-neoplastic agent. Suppresses bone marrow function and induces apoptotic cell death in non-melanoma skin cancer. IFN-α signaling is mediated by JAK1 and TYK2 tyrosine kinases. Note: 1 KU = 1000 units.
      Catalogue Number407293
      Brand Family Calbiochem®
      References
      ReferencesKrishnan, K., et al. 1997. Eur. J. Biochem. 247, 298.
      Rodriquez-Villanueva, S., and McDonnel, T.J. 1995. Int. J. Cancer 61, 110.
      Dianzani, F. 1993. Gut 34, 574.
      Brouty-Boyce, D., and Zetter, B.R. 1990. Science 208, 516.
      Sidky, Y.A., and Borden, E.C. 1987. Cancer Res. 47, 5155.
      Daugherty, B.L., and Pestka, S. 1986. Methods Enzymol. 119, 34.
      Pestka, S. 1986. Methods Enzymol. 119, 14.
      Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
      Johnson, M.D., et al. 1981. Methods Enzymol. 78, 394.
      Rubinstein, S., et al. 1981. J. Virol. 37, 755.
      Product Information
      Activity≥3.5 x 10⁴ units/ml
      Unit of DefinitionOne unit of interferon per ml of medium will cause a 50% inhibition of EMCV-induced cytopathic effect on mouse L929 cells. Units are determined with respect to the NIH international reference standard for mouse IFN-α.
      FormLiquid
      FormulationIn PBS containing 0.1% BSA.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      カタログ番号 GTIN
      407293-100KU 04055977188196

      Documentation

      α-Interferon, Mouse, Recombinant, E. coli (M)SDS

      タイトル

      英語版製品安全データシート((M)SDS) 

      α-Interferon, Mouse, Recombinant, E. coli 試験成績書(CoA)

      タイトルロット番号
      407293

      参考資料

      参考資料の概要
      Krishnan, K., et al. 1997. Eur. J. Biochem. 247, 298.
      Rodriquez-Villanueva, S., and McDonnel, T.J. 1995. Int. J. Cancer 61, 110.
      Dianzani, F. 1993. Gut 34, 574.
      Brouty-Boyce, D., and Zetter, B.R. 1990. Science 208, 516.
      Sidky, Y.A., and Borden, E.C. 1987. Cancer Res. 47, 5155.
      Daugherty, B.L., and Pestka, S. 1986. Methods Enzymol. 119, 34.
      Pestka, S. 1986. Methods Enzymol. 119, 14.
      Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
      Johnson, M.D., et al. 1981. Methods Enzymol. 78, 394.
      Rubinstein, S., et al. 1981. J. Virol. 37, 755.
      データシート

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-December-2008 JSW
      DescriptionRecombinant, mouse α-interferon expressed in E. coli. Antiviral, antineoplastic agent. Expressed during the triggering stage of macrophage cytocidal activation. Suppresses bone marrow function and cell proliferation. Modulates the immune response. Also known to induce apoptotic cell death in non-melanoma skin cancer.
      FormLiquid
      FormulationIn PBS containing 0.1% BSA.
      Purity≥95% by SDS-PAGE
      Activity≥3.5 x 10⁴ units/ml
      Unit definitionOne unit of interferon per ml of medium will cause a 50% inhibition of EMCV-induced cytopathic effect on mouse L929 cells. Units are determined with respect to the NIH international reference standard for mouse IFN-α.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      Merck USA index14, 4990
      ReferencesKrishnan, K., et al. 1997. Eur. J. Biochem. 247, 298.
      Rodriquez-Villanueva, S., and McDonnel, T.J. 1995. Int. J. Cancer 61, 110.
      Dianzani, F. 1993. Gut 34, 574.
      Brouty-Boyce, D., and Zetter, B.R. 1990. Science 208, 516.
      Sidky, Y.A., and Borden, E.C. 1987. Cancer Res. 47, 5155.
      Daugherty, B.L., and Pestka, S. 1986. Methods Enzymol. 119, 34.
      Pestka, S. 1986. Methods Enzymol. 119, 14.
      Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
      Johnson, M.D., et al. 1981. Methods Enzymol. 78, 394.
      Rubinstein, S., et al. 1981. J. Virol. 37, 755.

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      カテゴリー

      Life Science Research > タンパク質と酵素 > Other Proteins