MILLIPLEX MAPは研究領域別に分類されたパネル群と、それらに含まれる計900種以上のアナライトによって、マルチプレックスアッセイをサポートしています。
組み合わせが多様に亘るため、各パネルの使用実績や各種研究でどのようなアナライトが実際に使用されているのか、また、製品プロトコールに記載されている適用サンプル以外のサンプルでも測定は可能かどうか知りたい、という声を多数いただいていました。
本ページでは、そのようなご要望にお応えして、MILLIPLEX MAPが使用された文献の一部を「研究領域パネル」「疾患別」「特殊サンプル」のカテゴリに分けて紹介しています。
ご購入時やご使用の際に、是非ご参照・ご活用ください。
2.代謝パネル |
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RPTMAG-86K / Rat Pituitary Magnetic Bead Panel
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MMHMAG-44K / Mouse Metabolic Hormone Magnetic Bead Panel
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HMHEMAG-34K / Human Metabolic Hormone Magnetic Bead Panel
Hall K D, Bemis T, Brychta R, et al. Calorie for Calorie, Dietary Fat Restriction Results in More Body Fat Loss than Carbohydrate Restriction in People with Obesity[J]. Cell metabolism, 2015, 22(3): 427-436. (IF=17.565). (PMID: 26278052). [使用アナライト] |
3.シグナリングパネル |
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46-667MAG / GAPDH Total Magnetic Bead MAPmate
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48-660MAG / MAPK/SAPK Signaling 10-Plex Kit
Kano G, Almanan M, Bochner BS, et al. Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation |
48-680MAG / Multi-Pathway Magnetic Bead 9-Plex
Tisato V, Norcio A, Celeghini C, et al. Upregulation of SOCS-1 by Nutlin-3 in acute myeloid leukemia cells but not in primary normal cells [J].Clinics (Sao Paulo). 2014 Jan;69(1):68-74.(PMID: 24473562). [使用アナライト] |
1.食道がん |
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HCYTOMAG-60K / Human Cytokine/Chemokine Magnetic Bead Panel
Gastardelo T S, Cunha B R, Raposo L S, et al. Inflammation and cancer: role of annexin A1 and FPR2/ALX in proliferation and metastasis in human laryngeal squamous cell carcinoma |
2.乳がん |
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MCYTOMAG-70K / Mouse Cytokine/Chemokine Magnetic Bead Panel
Sousa S, Auriola S, Mönkkönen J, et al. Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells |
3.肺がん |
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48-650MAG / Human Src Family Kinase Active Site Kit
Sutton P, Borgia JA, Bonomi P, et al. Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells [J]. Mol Cancer. 2013 Jul 16;12:76. (PMID: 23866081) [使用アナライト] Lyn (Tyr397) |
4.膀胱がん |
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APOMAG-62K / Human Apolipoprotein Magnetic Bead Panel
Chen CL, Lin TS, Tsai CH, et al. Identification of potential bladder cancer markers in urine by abundant-protein depletion coupled with quantitative proteomics [J].J Proteomics. 2013 Jun 24;85:28-43. (PMID: 23631828). [使用アナライト] APOA1, APOA2, APOB, APOC2, APOC3, APOE |
5.膵臓がん |
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TGFBMAG-64K-01 / TGFß1 Magnetic Bead Single Plex Kit
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6.リンパ腫、白血病、自己免疫性リンパ増殖症候群(ALPS) |
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HCYTMAG-60K-PX38 / Human Cytokine/Chemokine Magnetic Bead Panel - Premixed 38 Plex
Blonska M, Zhu Y, Chuang H, et al. Jun-regulated genes promote interaction of diffuse large B-cell lymphoma with the microenvironment [J]. Blood, 2015, 125(6): 981-991. (PMID: 25533033) [使用アナライト] |
46-667MAG / GAPDH Total Magnetic Bead MAPmate,
48-650MAG / Human Src Family Kinase Active Site Kit, 48-680MAG / Multi-Pathway Magnetic Bead 9-Plex Ariës IM, Jerchel IS, van den Dungen RE, et al. EMP1, a novel poor prognostic factor in pediatric leukemia regulates prednisolone resistance, cell proliferation, migration and adhesion [J]. Leukemia. 2014 Sep;28(9):1828-37. (PMID: 24625531) [使用アナライト] |
48-680MAG / Multi-Pathway Magnetic Bead 9-Plex
Tisato V, Norcio A, Celeghini C, et al. Upregulation of SOCS-1 by Nutlin-3 in acute myeloid leukemia cells but not in primary normal cells [J].Clinics (Sao Paulo). 2014 Jan;69(1):68-74.(PMID: 24473562) [使用アナライト] |
MGAMMAG-300K / Mouse Immunoglobulin Isotyping Magnetic Bead Panel
Guo Q, Zhang J, Li J, Zou L, et al. Forced miR-146a expression causes autoimmune lymphoproliferative syndrome in mice via downregulation of Fas in germinal center B cells [J].Blood. 2013 Jun 13;121(24):4875-83. (PMID: 23645835) [使用アナライト] IgG1, IgG2a, IgG2b, IgG3 |
7.悪性黒色腫 |
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HCYP2MAG-62K / Human Cytokine/Chemokine Magnetic Bead Panel II
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8.卵巣がん |
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HCCBP1MAG-58K / Human Circulating Cancer Biomarker Magnetic Bead Panel
Pils D, Tong D, Hager G, et al. A combined blood based gene expression and plasma protein abundance signature for diagnosis of epithelial ovarian cancer--a study of the OVCAD consortium [J].BMC Cancer. 2013 Apr 3;13:178. (PMID: 23551967). [使用アナライト] MIF, prolactin, CA125, Leptin, osteopontin, IGF2 |
9.脳腫瘍 |
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46-667MAG / GAPDH Total Magnetic Bead MAPmate
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10.多発性硬化症 |
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HCVD2MAG-67K / Human Cardiovascular Disease (CVD) Magnetic Bead Panel 2
Tasset I, Bahamonde C, Agüera E, et al. Effect of natalizumab on oxidative damage biomarkers in relapsing-remitting multiple sclerosis [J].Pharmacol Rep. 2013;65(3):624-31. (PMID: 23950585) [使用アナライト] sVCAM-1, sICAM-1/sICAM |
MCD8MAG-48K / Mouse CD8 + T Cell Magnetic Bead Panel
Rainey-Barger EK, Blakely PK, Huber AK, et al. Virus-induced CD8+ T cells accelerate the onset of experimental autoimmune encephalomyelitis: implications for how viral infections might trigger multiple sclerosis exacerbations [J].J Neuroimmunol. 2013 Jun 15;259(1-2):47-54. (PMID: 23602715). [使用アナライト] |
12.免疫グロブリン サブタイプ解析 |
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HGAMMAG-301K / Human Isotyping Magnetic Bead Panel
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13.認知障害、精神疾患 |
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RSHMAG-69K / Rat Stress Hormone Magnetic Bead Panel
Justice N J, Huang L, Tian J B, et al. Posttraumatic Stress Disorder-Like Induction Elevates β-Amyloid Levels, Which Directly Activates Corticotropin-Releasing Factor Neurons to Exacerbate Stress Responses[J]. The Journal of Neuroscience, 2015, 35(6): 2612-2623. (PMID: 25673853) [使用アナライト] Corticosteroid/Corticosterone |
MBNMAG-41K / Mouse Bone Magnetic Bead Panel
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NHPPT1MG-46K / Non-Human Primate Pituitary Magnetic Bead Panel 1
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15.心疾患 |
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HADK1MAG-61K / Human Adipokine Magnetic Bead Panel 1
Schopfer DW, Ku IA, Regan M, et al. Growth differentiation factor 15 and cardiovascular events in patients with stable ischemic heart disease (The Heart and Soul Study) [J]. Am Heart J. 2014 Feb;167(2):186-192.e1.(PMID: 24439979). [使用アナライト] Adiponectin, Resistin |
HCYP2MAG-62K / Human Cytokine/Chemokine Magnetic Bead Panel II
Mansell H, Rosaasen N, Dean J, et al. Evidence of enhanced systemic inflammation in stable kidney transplant recipients with low Framingham risk scores [J]. Clin Transplant. 2013 Jul-Aug;27(4):E391-9. (PMID: 23782452). [使用アナライト] |
TGFBMAG-64K-01 / TGFß1 Magnetic Bead Single Plex Kit
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16.腎臓病 |
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HADK1MAG-61K / Human Adipokine Magnetic Bead Panel 1
Hung AM, Sundell MB, Plotnikova NE, et al. A pilot study of active vitamin D administration and insulin resistance in African American patients undergoing chronic hemodialysis |
HADK2MAG-61K / Human Adipokine Magnetic Bead Panel 2
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MGAMMAG-300K / Mouse Immunoglobulin Isotyping Magnetic Bead Panel
Lee SW, Park KH, Park S, et al. Soluble receptor for advanced glycation end products alleviates nephritis in (NZB/NZW)F1 mice [J]. Arthritis Rheum. 2013 Jul;65(7):1902-12. (PMID: 23553192). [使用アナライト IgG1, IgG2a, IgG2b, IgG3 |
17.毒性(心毒性) |
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HTMP2MAG-54K / Human TIMP Magnetic Bead Panel 2
Herrmann JE, Heale J, Bieraugel M, et al. Isoproterenol effects evaluated in heart slices of human and rat in comparison to rat heart in vivo [J]. Toxicol Appl Pharmacol. 2014 Jan 15;274(2):302-12. (PMID: 24286936). [使用アナライト] TIMP-1, TIMP-2, TIMP-3, TIMP-4 |
18.乾癬 |
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HCVD2MAG-67K / Human Cardiovascular Disease (CVD) Magnetic Bead Panel 2
Sigurdardottir G, Ekman AK, Ståhle M, et al. Systemic treatment and narrowband ultraviolet B differentially affect cardiovascular risk markers in psoriasis [J]. J Am Acad Dermatol. 2014 Jun;70(6):1067-75. (PMID: 24656729). [使用アナライト] sVCAM-1, sICAM-1, sE-selectin/sP-Selectin, MPO |
19.睡眠時無呼吸症候群 |
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HIGFMAG-52K / Human IGF-I, II Magnetic Bead Panel
Fung AM, Wilson DL, Lappas M, et al. Effects of maternal obstructive sleep apnoea on fetal growth: a prospective cohort study [J]. PLoS One. 2013 Jul 24;8(7):e68057. (PMID: 23894293). [使用アナライト] IGF-1, IGF-2 |
20.疼痛 |
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HNPMAG-35K / Human Neuropeptide Magnetic Bead Panel
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21.黄熱病 |
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HCVD3MAG-67K / Human Cardiovascular Disease (Acute Phase) Magnetic Bead Panel 3
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22.生殖・精子形成 |
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MPTMAG-49K / Mouse Pituitary Magnetic Bead Panel
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1.組織ライセート |
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下垂体腺
RPTMAG-86K / Rat Pituitary Magnetic Bead Panel |
腎臓
PCYTMAG-23K / Porcine Cytokine/Chemokine Magnetic Bead Panel Gardner D S, De Brot S, Dunford L J, et al. Remote conditioning or erythropoietin before surgery primes kidneys to clear ischemia-reperfusion-damaged cells: a renoprotective mechanism? [J]. Am J Physiol Renal Physiol. 2014 Apr 15; 306(8): F873–F884. (PMID: 24523383). [使用アナライト] IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-10, IL-12, IL-18, TNF-α |
2.末梢血単核細胞 |
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Boswell K L, Paris R, Boritz E, et al. Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection [J]. PLoS pathogens, 2014, 10(1). (PMID: 24497824). [使用アナライト] |
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