Key insights on lipid excipients for their use in RNA delivery
（和訳：「RNAデリバリーに使用される重要な脂質原料」）

発表要旨

Beyond the Covid-19 pandemic, there is continued growth around nucleic acid-based vaccines and therapeutics as new formulations are being evaluated for a wider range of indications. With lipid-based systems remaining the established method for the efficient delivery of RNA, this presentation covers key insights on lipids excipients that should be considered early in the drug development process to optimize the performance, reproducibility, costs, and regulatory timelines of the final drug product.

プロフィール

Estelle Beguin holds a PhD in Engineering Science from the University of Oxford, U.K. where she worked on developing ultrasound-responsive lipid-based drug delivery systems. With experience working as a formulation and process engineer on drug delivery programs for several biotech companies in Boston, she joined Merck as the global Strategic Marketing Manager for synthetic lipids. In her current role, she is responsible for managing Merck’s lipids portfolio and custom manufacturing businesses supporting top industry players and young start-ups in the fields of RNA delivery and vaccines.