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501890 Vitamin K₁ (phytomenadione)

EMPROVE® ESSENTIAL Ph Eur,BP,USP,FCC

Vitamin K₁ (phytomenadione) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Methyl-3-phytyl-1,4-naphthoquinone

CAS #: 84-80-0 EC Number: 201-564-2 Molar Mass: 450.71 g/mol Hill Formula: C₃₁H₄₆O₂ Grade: Ph Eur,BP,USP,FCC
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501890
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
84-80-0201-564-2C₃₁H₄₆O₂450.71 g/molPh Eur,BP,USP,FCC

Pricing & Availability

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5.01890.0001
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      		 Glass bottle 1 g
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      5.01890.0100
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          		 Alu bottle 100 g
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          Description
          Catalogue Number501890
          Synonyms2-Methyl-3-phytyl-1,4-naphthoquinone
          References
          Product Information
          CAS number84-80-0
          EC number201-564-2
          GradePh Eur,BP,USP,FCC
          Hill FormulaC₃₁H₄₆O₂
          Molar Mass450.71 g/mol
          HS Code2936 29 40
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Boiling point140 - 145 °C (0.0013 hPa)
          Density0.984 g/cm3 (20 °C)
          Melting Point-20 °C
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat > 33487 mg/kg
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +15°C to +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDKein Gefahrgut
          Declaration (transport by air) IATA-DGRNo Dangerous Good
          Declaration (transport by sea) IMDG-CodeNo Dangerous Good
          Supplemental Information
          Specifications
          Assay (HPLC, Ph Eur): trans-phytomenadione≥ 85.0 %
          Assay (HPLC, Ph Eur): sum of trans-phytomenadione,cis-phytomenadione and trans-epoxyphytomenadione97.0 - 103.0 %
          Assay (HPLC, USP)97.0 - 103.0 %
          Identity (IR-spectrum)passes test
          Identity (UV-absorption, Ph Eur)passes test
          Identity (UV-absorption, USP)passes test
          Identity (HPLC)passes test
          Identity (optical rotation)passes test
          Appearanceclear, yellow, viscous, oily liquid
          Appearance of solution (100 g/l; trimethylpentane)clear
          Neutral reactionpasses test
          Refractive index (n 25/D)1.523 - 1.526
          Optical rotation-0.05 - 0.05 °
          As (Arsenic)≤ 3 ppm
          Cu (Copper)≤ 25 ppm
          Pb (Lead)≤ 2 ppm
          Zn (Zinc)≤ 25 ppm
          Related substances (HPLC, Ph Eur) (Impurity B)≤ 0.2 %
          Related substances (HPLC, Ph Eur)(any unspecified impurities)≤ 0.15 %
          Related substances (HPLC, Ph Eur) (Sum of all impurities)≤ 1.0 %
          cis-phytomenadione (HPLC, USP)≤ 21.0 %
          Menadione (USP)passes test
          Menadione (TLC, Ph Eur)≤ 0.2 %
          Acetone (HS-GC)≤ 500 ppm
          ethyl ether (HS-GC)≤ 500 ppm
          Methanol (HS-GC)≤ 300 ppm
          Petroleum ether (HS-GC)≤ 290 ppm
          Toluene (HS-GC)≤ 890 ppm
          Other residual solvents (ICH Q3C)excluded by production process
          Acid value≤ 2.0
          Sulfated ash (600 °C)≤ 0.1 %
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph Eur, BP, USP, FCC
          Global Trade Item Number
          Catalogue Number GTIN
          5.01890.0001 04022536258683
          5.01890.0100 04022536258690

          Documentation

          Material Qualification Dossier

          TitleVersion
          9.0

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          Vitamin K₁ (phytomenadione) SDS

          Title

          Safety Data Sheet (SDS) 

          Vitamin K₁ (phytomenadione) Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          5.01890.0001 Glass bottlePDF Specification Document
          5.01890.0100 Alu bottlePDF Specification Document

          Certificates

          Title