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Merck

598250

THP

A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT.

Synonym(s):

THP, Tris(hydroxypropyl)phosphine

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About This Item

Empirical Formula (Hill Notation):
C9H21O3P
CAS Number:
4706-17-6
Molecular Weight:
208.24
UNSPSC Code:
12352128
NACRES:
NA.25
MDL number:
MFCD00269835

Key Documents

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Product Name

THP, A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT.

SMILES string

P(CCCO)(CCCO)CCCO

InChI

1S/C9H21O3P/c10-4-1-7-13(8-2-5-11)9-3-6-12/h10-12H,1-9H2

InChI key

YICAEXQYKBMDNH-UHFFFAOYSA-N

assay

≥80% (31P-NMR)

form

viscous liquid

reaction suitability

reagent type: reductant

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

colorless

solubility

water: 20 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Related Categories

Disclaimer

Toxicity: Corrosive (L)

General description

A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT. THP is comparable with TCEP (Cat. No. 580560) as a reducing agent. Its reduction capacity against oxidized glutathione is 0.232 meq/g (Note: TCEP has a reduction capacity of 0.182 meq/g). THP is also more resistant to air oxidation as compared to DTT.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

pictograms

Corrosion
GHS05

hcodes

H314

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
598250-1GMCN04055977189179

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