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FCMAB170F Milli-Mark Anti-CD4 -FITC Antibody, clone MT310

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FCMAB170F
100 tests  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMFITCMonoclonal Antibody
      Description
      Catalogue NumberFCMAB170F
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark Anti-CD4 -FITC Antibody, clone MT310
      Alternate Names
      • T-cell surface antigen T4/Leu-3
      Background InformationCD4 is a 55 kDa glycoprotein with four immunoglobulin-like external domains, a transmembrane domain and a highly conserved intracellular domain (Leong, 1999). CD4 acts as a coreceptor in MHC class II-restricted antigen-induced T-cell activation. Further, CD4 has a role in the regulation of T-B lymphocyte adhesion in the absence of antigen recognition, and in thymic differentiation (Piatier-Tonneau, 2002). CD4 is expressed on thymocyte subsets, it marks helper/inducer T cells, and it is expressed in 55-65% of mature peripheral T cells. Subpopulations of suppressor or cytotoxic T cells can be identified among CD4-positive T cells. CD4 is also expressed on monocytes/macrophages, Langerhans cells and other dendritic cells. CD4 is not expressed on B cells. Anti-CD4, MT310, was included in the Second International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with the CD4 antigen (Miedema, 1986).
      References
      Product Information
      FormatFITC
      HS Code3002 15 90
      Control
      • Human Lymphocytes
      PresentationPurified Mouse monoclonal IgG1 kappa conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
      Quality LevelMQ100
      Applications
      ApplicationMilli-Mark Anti-CD4 -FITC Antibody, clone MT310 is an antibody against CD4 for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      CloneMT310
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD4 antigen.
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight 55 kDa (Leong, 1999)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using human lymphocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      FCMAB170F 04053252746260

      Documentation

      Milli-Mark Anti-CD4 -FITC Antibody, clone MT310 SDS

      Title

      Safety Data Sheet (SDS) 

      Milli-Mark Anti-CD4 -FITC Antibody, clone MT310 Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-CD4 -FITC, clone MT310 - 2141848 2141848
      Milli-Mark Anti-CD4 -FITC, clone MT310 - 2145103 2145103
      Milli-Mark Anti-CD4 -FITC, clone MT310 - NRG1762712 NRG1762712
      Milli-Mark Anti-CD4 -FITC, clone MT310 - 2266750 2266750
      Milli-Mark™ Anti-CD4 -FITC -2514237 2514237
      Milli-Mark™ Anti-CD4 -FITC, -2676645 2676645
      Milli-Mark™ Anti-CD4 -FITC, clone MT310 2487756
      Milli-Mark™ Anti-CD4 -FITC, clone MT310 - 3614132 3614132
      Milli-Mark™ Anti-CD4 -FITC, clone MT310 Conjugate 3052524
      Milli-Mark™ Anti-CD4 -FITC,clone MT310 -2681326 2681326

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies