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444241 MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem

The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors application

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MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid

Primary Target: MMP-2, MMP-9
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444241
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Overview

Key Spec Table

CAS #Empirical Formula
193807-58-8C₂₁H₁₉NO₄S

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      Description
      OverviewA potent inhibitor of MMP-2 (IC50 = 310 nM) and MMP-9 (IC50 = 240 nM). Orally active in animal models of tumor growth and metastasis.
      Catalogue Number444241
      Brand Family Calbiochem®
      Synonyms(2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
      References
      ReferencesTamura, Y., et al. 1998. J. Med. Chem. 41, 640.
      Product Information
      CAS number193807-58-8
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₁H₁₉NO₄S
      Chemical formulaC₂₁H₁₉NO₄S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetMMP-2, MMP-9
      Primary Target IC<sub>50</sub>310 nM and 240 nM against MMP-2 and MMP-9
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      444241-5MGCN 07790788056384