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MTH17MAG-47K

MILLIPLEX® Mouse TH17 Panel

Configurable Mouse Th17 25-Plex Panel

Synonym(s):

Millipore Mouse Immunology Panel, Mouse Immunology Protein Multiplex Assay, murine Th17 assay

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Product Name

MILLIPLEX® Mouse TH17 Panel,

species reactivity

mouse

Quality Segment

200

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

linearity: 111.0%
(1:04), linearity: 113.1%
(1:08), standard curve range: 1.5-1,500 pg/mL
(IL-4), standard curve range: 10-10,000 pg/mL
(IL-17F), standard curve range: 127-130,000 pg/mL
(IL-28B), standard curve range: 15-15,000 pg/mL
(IL-1β), standard curve range: 2.4-2,500 pg/mL
(IL-22), standard curve range: 20-20,000 pg/mL
(IL-10, IL-12(p70), & IL-21), standard curve range: 3.4-3,500 pg/mL
(TNFα), standard curve range: 34-35,000 pg/mL
(GM-CSF & IL-15), standard curve range: 342-350,000 pg/mL
(IL-23), standard curve range: 39-40,000 pg/mL
(IL-13 & IL-17A), standard curve range: 4.9-5,000 pg/mL
(IL-5), standard curve range: 488-500,000 pg/mL
(TNFβ), standard curve range: 49-50,000 pg/mL
(CD40L IL-31 & MIP-3α), standard curve range: 586-600,000 pg/mL
(IL-17E/ IL-25), standard curve range: 6.9-6,000 pg/mL
(IL-2), standard curve range: 7.8-8,000 pg/mL
(IFNγ & IL-6), standard curve range: 78-80,000 pg/mL
(IL-33), standard curve range: 879-900,000 pg/mL
(IL-27)

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)
serum
plasma

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Th17 cells, a subset of CD4+ T helper cells, play a crucial role in immune responses by producing a range of cytokines, particularly interleukin-17 (IL-17). In mice, Th17 cytokines, including IL-17A, IL-17F, and IL-22, are involved in promoting inflammation and are key players in the defense against extracellular pathogens, as well as in the pathogenesis of autoimmune diseases. These cytokines help to recruit neutrophils and enhance the production of antimicrobial peptides, contributing to the host′s immune response.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 25 analytes in mouse serum, plasma, and cell culture supernatants.

Analytes included: CD40 Ligand, GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-15, IL-17A, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27, IL-28B, IL-31, IL-33, MIP-3α/CCL20, TNF-α, TNFβ

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Comprehensive Th17 Profiling: Simultaneously measures a wide range of Th17-related cytokines and chemokines, including IL-17A, IL-17F, IL-21, IL-22, IL-23, and more—ideal for studying autoimmune and inflammatory pathways.

Minimal Sample Volume Required: Optimized for small sample inputs, making it perfect for mouse models and limited biological material.

Multiplex Efficiency with Luminex® xMAP® Technology: Magnetic bead-based format allows simultaneous detection of multiple analytes in a single well, saving time, reagents, and sample volume.

Validated for Mouse Samples: Designed specifically for mouse serum, plasma, and cell culture supernatants, ensuring compatibility and performance in preclinical studies.

Ideal for Autoimmune and Cancer Research: Supports investigation into Th17 cell roles in diseases such as rheumatoid arthritis, Crohn’s disease, diabetes, and cancer progression.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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signalword

Danger

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

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pdsc

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prtr

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fsl

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ishl_indicated

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ishl_notified

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Certificates of Analysis (COA)

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