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MILLIPLEX® Human Soluble Cytokine Receptor Panel

Configurable Human Soluble Cytokine Receptor 14-Plex Panel

Synonym(s):

Human Cytokine Receptor Multiplex Kit, Luminex® Human Cytokine Receptor Immunoassay, Millipore Cytokine Receptor Panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Product Name

MILLIPLEX® Human Soluble Cytokine Receptor Panel,

Quality Segment

200

description

Configurable Human Soluble Cytokine Receptor 14-Plex Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

plasma
serum
cell culture supernatant(s)

assay range

accuracy: 91-104%, sensitivity: 4-208 pg/mL
(Overnight Incubation minDC), standard curve range: 12.2-50,000 pg/mL
(sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII), standard curve range: 122.1-500,000 pg/mL
(sEGFR, sIL-1RII, sVEGF-R1, sVEGF-R2, sVEGF-R3), standard curve range: 24.4-100,000 pg/mL
(sCD30, sgp130, sIL-1RI, sIL-2Rα), inter-assay cv: <15%
intra-assay cv: <10%

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Cytokine receptors constitute an integral part of cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane- bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors can inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 14 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: sCD30, sEGFR, sGP130, sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII, sVEGFR1, sVEGFR2, sVEGFR3

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Multiplex Capability: The panel allows for the simultaneous quantification of 14 soluble cytokine receptors, enhancing efficiency in data collection.
  • Supports Inflammation and Immunology Research: This panel is particularly useful in studies related to inflammation and immunology, aiding researchers in understanding disease mechanisms and developing potential immunotherapeutic agents.
  • Configurable Panel Options: Offers flexibility to tailor the panel to specific research needs or disease models.
  • Backed by Scientific Support: Comes with expert technical assistance and detailed documentation to guide experimental design and data interpretation.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

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prtr

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fsl

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ishl_notified

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Certificates of Analysis (COA)

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