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100286 L-Glutamine

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
56-85-9200-292-1C₅H₁₀N₂O₃146.15 g/molDAB,JP,USP

Pricing & Availability

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1.00286.1000
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      Plastic bottle 1 kg
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      1.00286.9010
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          Description
          Catalogue Number100286
          SynonymsL-Glutamic acid-5-amide, Gln
          References
          Product Information
          CAS number56-85-9
          EC number200-292-1
          GradeDAB,JP,USP
          Hill FormulaC₅H₁₀N₂O₃
          Molar Mass146.15 g/mol
          HS Code2924 19 99
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Density1.47 g/cm3 (20 °C)
          Melting Point185 - 186 °C
          pH value5.0 - 6 (14.6 g/l, H₂O, 25 °C)
          Vapor pressure<0.1 hPa (25 °C)
          Bulk density640 kg/m3
          Solubility100 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 7500 mg/kg
          Safety Information according to GHS
          RTECSMA2275100
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +30°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
          Identity (IR-spectrum)passes test
          Identity (specific rotation)passes test
          Appearancewhite to almost white, fine powder
          Appearance of solution (25 g/l; CO₂-free water)clear and colorless
          Spec. rotation (α 20/D, 100 g/l, hydrochloric acid 2 mol/l, calc. on dried substance)+31.5 to +33.0
          Spec. rotation (α 20/D, 40 g/l, water, calc. on dried substance)+6.3 to +7.3
          pH (25 g/l; CO₂-free water)4.0 - 6.0
          pH (20 g/l, CO₂-free water)4.5 - 6.0
          Chloride (Cl)≤ 200 ppm
          Sulfate (SO₄)≤ 200 ppm
          Heavy metals (as Pb)≤ 10 ppm
          Cu (Copper)≤ 25 ppm
          Fe (Iron)≤ 10 ppm
          Mn (Manganese)≤ 25 ppm
          Ni (Nickel)≤ 2 ppm
          Zn (Zinc)≤ 130 ppm
          NH₄ (Ammonium)≤ 0.1 %
          Ninhydrin - positive substances (TLC)≤ 0.5 %
          Related substances (TLC)passes test
          Residual solvents (ICH Q3C)excluded by manufacturing process
          Sulfated ash (600 °C)≤ 0.1 %
          Loss on drying (105 °C; 3 h)≤ 0.3 %
          Bacterial endotoxins≤ 2.0 I.U./g
          Microbiological test (total aerobic microbial count (TAMC))≤ 10²
          Microbiological test (total yeast and mould count (TYMC))≤ 10²
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to DAB, JP, USP
          Global Trade Item Number
          Catalogue Number GTIN
          1.00286.1000 04022536906720
          1.00286.9010 04022536906737

          Documentation

          Material Qualification Dossier

          TitleVersion
          6.0

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          L-Glutamine SDS

          Title

          Safety Data Sheet (SDS) 

          L-Glutamine Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1.00286.1000 Plastic bottlePDF Specification Document
          1.00286.9010 Plastic drumPDF Specification Document

          Certificates

          Title

          Brochure

          Title
          Cellvento®4CHO
          バイオ医薬品製造用製品ガイド