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SCC199 HGT-1 Human Gastric Cancer Cell Line

HGT-1 human gastric cancer cell line is a suitable model for a wide range of characterization and tumorigenic studies.

SCC199
≥1X10⁶ cells/vial   
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      Overview

      Replacement Information
      Description
      Catalogue NumberSCC199
      DescriptionHGT-1 Human Gastric Cancer Cell Line
      OverviewThe HGT-1 human gastric cancer cell line is derived from a poorly-differentiated adenocarcinoma and is well-established as a model for studies of gastric cancer and mechanisms of gastric secretion. HGT-1 cells are tumorigenic in nude mice and have a hyperdiploid karyotype (2). HGT-1 cells do not secrete mucus, yet maintain expression of functional histamine H2 receptors also found in normal acid-secreting parietal cells (2).

      Source:
      The HGT-1 cell line was established from a primary tumor of a 60-year-old male patient (2).
      Alternate Names
      • HGT1
      Background InformationGastric adenocarcinoma is the most common type of gastric cancer, representing 95% of malignancies that originate in the stomach (1). The incidence of gastric adenocarcinoma is especially high in Central and Eastern Asia and areas of Eastern Europe and South America, comprising a significant global health burden (1). Robust models of gastric cancer that reflect the most prevalent form of this disease are therefore highly valuable.

      References:
      1. Nat Rev Dis Primers 2017; 3: 17036.
      2. Cancer Res 1982; 42(4): 1541-1548.
      References
      Product Information
      Applications
      ApplicationHGT-1 human gastric cancer cell line is a suitable model for a wide range of characterization and tumorigenic studies.
      Key Applications
      • Cell Culture
      Application NotesThis product is sold solely for research use per the terms of the “Restricted Use Agreement” which govern its use as detailed in the product Data Sheet or Certificate of Analysis. For information regarding any other use, please contact licensing@emdmillipore.com.
      Biological Information
      Cell Line Type
      • Cancer Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assurance• Each vial contains ≥ 1X10⁶ viable cells.
      • Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
      • Cells are verified to be of human origin and negative for inter-species contamination from rat, mouse, chinese hamster, Golden Syrian hamster, and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
      • Cells are negative for mycoplasma contamination.
      • Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
      Packaging Information
      Material Size≥1X10⁶ cells/vial
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCC199 04054839752841