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852287 Fmoc-p-Bz-Phe-OH

Fmoc-p-Bz-Phe-OH Fmoc-L-p-benzoylphenylalanine Novabiochem®. CAS 117666-96-3, molar mass 491.53 g/mol.

Fmoc-p-Bz-Phe-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 117666-96-3 Molar Mass: 491.50 g/mol Hill Formula: C₃₁H₂₅NO₅
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
117666-96-3C₃₁H₂₅NO₅491.50 g/mol

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      8.52287.0005
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          Description
          Catalogue Number852287
          Brand Family Novabiochem®
          Alternate Names
          • (S)-3-(4-Benzoyl-phenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid,4-Benzoyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]phenylalanine
          Background InformationFmoc-p-Bz-Phe-OH-OH is a useful tool for preparing photoactivatable peptide-based affinity probes [1]. On photolysis at 366 nm, Benzoylphenylalanine (Bpa) generates a biradical that has a preference for insertion into C-H bonds, particularly those of Leu, Val and Met side chains.

          The derivative can be introduced using standard coupling method such as PyBOP and is stable to conditions used in peptide chain extension. For the cleavage of Bpa containing peptide from the resin, the use of thiols and silanes should be avoided as dithioketal formation and reduction, respectively, have been observed.
          References
          Product Information
          CAS number117666-96-3
          Hill FormulaC₃₁H₂₅NO₅
          Molar Mass491.50 g/mol
          HS Code2924 29 70
          Structure formula ImageStructure formula Image
          Quality LevelMQ200
          Applications
          ApplicationFmoc-p-Bz-Phe-OH Fmoc-L-p-benzoylphenylalanine Novabiochem®. CAS 117666-96-3, molar mass 491.53 g/mol.
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 3 highly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +8°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Colour (visual)white to slight yellow to beige
          Appearance of substance (visual)powder
          Identity (IR)passes test
          Optical rotation α 25/D (c=1 in DMF)-31.0 - -27.0 °
          Assay (HPLC, area%)≥ 98.0 % (a/a)
          Solubility (1 mmole in 2 ml DMF)clearly soluble
          Global Trade Item Number
          Catalogue Number GTIN
          8.52287.0001 04027269194901
          8.52287.0005 04027269194918

          Documentation

          Fmoc-p-Bz-Phe-OH SDS

          Title

          Safety Data Sheet (SDS) 

          Citations

          Title
          [1] K. T. O'Neil, et al. (1989) J. Biol. Chem., 264.