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344905 FURA 2/AM - CAS 108964-32-5 - Calbiochem

Cell-permeable ester form of FURA 2.

FURA 2/AM - CAS 108964-32-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester

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344905
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344905-1MGCN
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      344905-1SETCN
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          Description
          OverviewCell-permeable ester form of FURA 2. Note: 1 set = 10 x 100 µg.
          PLURONIC® F-127, PROTEIN GRADE® Detergent (Cat. No. 540025, available separately) is a mild, low-toxicity detergent that can aid in the solubilization of FURA 2/AM.
          Catalogue Number344905
          Brand Family Calbiochem®
          Synonyms1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester
          References
          ReferencesDavis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
          Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
          Schwartz, Y., et al. 1992. Endocrinology 131, 772.
          Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
          Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
          Tsien, R.Y. 1980. Biochemistry 19, 2396.
          Product Information
          CAS number108964-32-5
          ATP CompetitiveN
          FormYellow solid
          Hill FormulaC₄₄H₄₇N₃O₂₄
          Chemical formulaC₄₄H₄₇N₃O₂₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetRatiometric calcium indicator
          Purity≥95% by HPLC.
          Physicochemical Information
          Cell permeableY
          Emission max.
          Excitation max.
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          344905-1MGCN 04055977214895
          344905-1SETCN 04055977214901

          Documentation

          FURA 2/AM - CAS 108964-32-5 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          FURA 2/AM - CAS 108964-32-5 - Calbiochem Certificates of Analysis

          TitleLot Number
          344905

          References

          Reference overview
          Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
          Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
          Schwartz, Y., et al. 1992. Endocrinology 131, 772.
          Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
          Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
          Tsien, R.Y. 1980. Biochemistry 19, 2396.

          Brochure

          Title
          Caspases and other Apoptosis Related Tools Brochure
          Fluorescent Calcium Probes Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision27-June-2008 RFH
          Synonyms1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester
          DescriptionCell permeant ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (Kd = 224 nM) that offers 30 times greater fluorescence intensity than QUIN 2 (Cat. No. 551826). Can be used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm). Note: 1 set = 10 x 100 µg.
          FormYellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number108964-32-5
          Chemical formulaC₄₄H₄₇N₃O₂₄
          Structure formulaStructure formula
          Purity≥95% by HPLC.
          SolubilityDMSO (10 mg/ml). Further dilute with aqueous buffers just prior to use.
          Storage Protect from light
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          ReferencesDavis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
          Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
          Schwartz, Y., et al. 1992. Endocrinology 131, 772.
          Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
          Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
          Tsien, R.Y. 1980. Biochemistry 19, 2396.

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          Categories

          Life Science Research > Inhibitors and Biochemicals