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341006 EDAC, Hydrochloride

EDAC HCl is a water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis.

EDAC, Hydrochloride MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: EDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl

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341006
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Overview

Replacement Information

Key Spec Table

CAS #Purity
25952-53-8≥98% by Titration

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341006-25GMCN
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      341006-5GMCN
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          Description
          OverviewWater-soluble carbodiimide derivative. Used to modify NMDA receptors. Also useful for conjugating haptens to proteins or polypeptides.
          Molar absorptivity (~212 nm; 50 mM phosphate buffer, pH 8):≥6800 M-1cm-1.
          Catalogue Number341006
          Brand Family Calbiochem®
          SynonymsEDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
          References
          ReferencesChazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
          Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
          Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
          Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
          Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
          Yamada, H., et al. 1981. Biochemistry 20, 4836.
          Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
          Ozawa, H. 1970. Biochemistry 9, 2158.
          Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.
          Product Information
          CAS number25952-53-8
          FormWhite solid
          Hill FormulaC₈H₁₇N₃ · HCl
          Chemical formulaC₈H₁₇N₃ · HCl
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Quality LevelMQ200
          Applications
          Biological Information
          Purity≥98% by Titration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSFF2200000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage -20°C
          Protect from Moisture Protect from moisture
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsUnstable in solution. Reconstitute just prior to use.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          341006-25GMCN 07790788054182
          341006-5GMCN 04055977215403

          Documentation

          EDAC, Hydrochloride SDS

          Title

          Safety Data Sheet (SDS) 

          EDAC, Hydrochloride Certificates of Analysis

          TitleLot Number
          341006

          References

          Reference overview
          Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
          Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
          Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
          Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
          Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
          Yamada, H., et al. 1981. Biochemistry 20, 4836.
          Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
          Ozawa, H. 1970. Biochemistry 9, 2158.
          Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.

          Brochure

          Title
          Excitotoxic Glutamate Analogs Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision17-October-2017 JSW
          SynonymsEDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
          DescriptionWater-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis. The major advantage of EDAC coupling is the easy removal of excess reagent and the corresponding urea by washing with dilute acid or water. Carbodiimides catalyze the formation of amide bonds, carboxylic acids, and amines by activating the carboxylate to form an O-acylurea. This intermediate can be attacked by an amine directly to form an amide. EDAC is released as a soluble urea derivative.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number25952-53-8
          RTECSFF2200000
          Chemical formulaC₈H₁₇N₃ · HCl
          Structure formulaStructure formula
          Purity≥98% by Titration
          SolubilityH₂O (2-5 mg/ml) or Aqueous buffers (2-5 mg/ml). Avoid amine containing buffers.
          Storage Protect from moisture
          -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsUnstable in solution. Reconstitute just prior to use.
          Toxicity Irritant
          ReferencesChazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
          Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
          Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
          Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
          Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
          Yamada, H., et al. 1981. Biochemistry 20, 4836.
          Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
          Ozawa, H. 1970. Biochemistry 9, 2158.
          Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.