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165304 D-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.

D-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: D-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate

Primary Target: NMDA receptor antagonist
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165304
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
79055-68-8C₅H₁₂NO₅P

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      Description
      OverviewActive enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. Also inhibits the capsaicin-induced release of substance P from spinal cord.
      Catalogue Number165304
      Brand Family Calbiochem®
      SynonymsD-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate
      References
      ReferencesMalcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
      Schulte, M.K., et al. 1994. Brain Res. 649, 203.
      Davis, S., et al. 1992. J. Neurosci. 12, 21.
      Product Information
      CAS number79055-68-8
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₅H₁₂NO₅P
      Chemical formulaC₅H₁₂NO₅P
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetNMDA receptor antagonist
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      165304-5MGCN 04055977207668

      Documentation

      D-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      D-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      165304

      References

      Reference overview
      Malcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
      Schulte, M.K., et al. 1994. Brain Res. 649, 203.
      Davis, S., et al. 1992. J. Neurosci. 12, 21.

      Brochure

      Title
      Pathways and Biomarkers of Glutamatergic Synapse Flyer
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-April-2008 RFH
      SynonymsD-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate
      DescriptionActive enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used competitive NMDA receptor antagonist.
      FormWhite solid
      CAS number79055-68-8
      Chemical formulaC₅H₁₂NO₅P
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDilute Aqueous Base (1 mg/ml) or H₂O (1 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Irritant
      ReferencesMalcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
      Schulte, M.K., et al. 1994. Brain Res. 649, 203.
      Davis, S., et al. 1992. J. Neurosci. 12, 21.