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204902 Complement C5a des-Arg, Human

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204902
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204902-30UGCN
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      Plastic ampoule 30 μg
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      Description
      OverviewNative, human des-Arg C5a complement component. Single chain glycopeptide composed of 73 amino acids. Once the C5a glycopeptide has been produced in human plasma or serum, it is rapidly converted to C5a des-Arg upon removal of the C-terminal arginine by the endogenous serum carboxypeptidase N. Unlike the C3a des-Arg peptide, C5a des-Arg retains significant levels of its biological activities. Thus, C5a des-Arg has been shown to exhibit inflammatory cell chemotaxis, smooth muscle contraction, and leukotriene release from guinea pig lung.
      Catalogue Number204902
      Brand Family Calbiochem®
      References
      ReferencesWebster, R.O., et al. 1980. Immunopharmacology 1, 201.
      McCarthy, K. and Henson, P.M. 1979. J. Immunol. 123, 2511.
      Product Information
      FormLiquid
      FormulationIn 120 mM NaCl, 10 mM HEPES, pH 7.2.
      Quality LevelMQ100
      Biological Information
      Purity≥90% by SDS-PAGE
      SourcePrepared from plasma of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Concentration Label Please refer to vial label for lot-specific concentration
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      204902-30UGCN 04055977219869