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EZCCP-47K Canine C-peptide ELISA

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EZCCP-47K
96-well strip plate  
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      Overview

      Replacement Information

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      C-Peptide CaELISAFluorescent Colorimetric
      Description
      Catalogue NumberEZCCP-47K
      DescriptionCanine C-peptide ELISA
      Background InformationC-peptide is a byproduct of normal insulin production by the beta cells in the pancreas and correlates directly to endogenous concentrations of insulin.
      References
      Product Information
      Detection methodFluorescent Colorimetric
      Precision, %
      • Inter Assay: <15%
      • Intra Assay:<10%
      Quality LevelMQ200
      Applications
      ApplicationThis Canine C-Peptide ELISA is used to measure & quantify C-Peptide levels in Metabolism & Endocrine research.
      Key Applications
      • ELISA
      Application Notes3 hour assay, room temperature 20 μL sample size
      Biological Information
      Species Reactivity
      • Canine
      Analytes Available
      • C-Peptide
      Entrez Gene Number
      Entrez Gene SummaryAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.
      Gene Symbol
      • INS
      • proinsulin
      • insulin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      SIZE: 110 amino acids; 11981 Da
      SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
      SUBCELLULAR LOCATION: Secreted.
      DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
      SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.
      Accuracy
      • 95%
      Physicochemical Information
      Sensitivity
      • 0.24 ng/mL
      Linearity of Dilution96-118%
      Standard Curve Range
      • 0.2-10 ng/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • For research use only. Not for use in diagnostic procedures.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      EZCCP-47K 04055977315363