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189513 Autotaxin Inhibitor IV, HA155 - CAS 1312201-00-5 - Calbiochem

The Autotaxin Inhibitor IV, HA155 controls the biological activity of Autotaxin. This small molecule/inhibitor is primarily used for Cell Structure applications.

Autotaxin Inhibitor IV, HA155 - CAS 1312201-00-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Atx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid

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189513
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Overview

Key Spec Table

CAS #Empirical Formula
1312201-00-5C₂₄H₁₉BFNO₅S

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189513-10MGCN
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      Description
      OverviewA ~5-fold more potent (IC50 = 5.7 nM) para-isomer boronate analog of Autotaxin Inhibitor II, HA130 (Cat. No. 189511) that efficiently blocks thrombin-stimulated lysophosphatidic acid secretion in platelets and in mammalian cells.
      Catalogue Number189513
      Brand Family Calbiochem®
      SynonymsAtx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid
      References
      ReferencesFulkerson, Z., et al. 2011. J. Biol. Chem. 286, 34654.
      Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol. 18, 198.
      Albers, H.M.H.G., et al. 2011. J. Med. Chem. 54, 4619.
      Albers, H.M.H.G., et al. 2010. J. Med. Chem. 53, 4958.
      Product Information
      CAS number1312201-00-5
      FormYellow powder
      Hill FormulaC₂₄H₁₉BFNO₅S
      Chemical formulaC₂₄H₁₉BFNO₅S
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥99% by HPLC
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      189513-10MGCN 04055977221893