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ABN475 Anti-Wnt Antibody-10b

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ABN475
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN475
      DescriptionAnti-Wnt Antibody-10b
      Alternate Names
      • Protein Wnt-10b
      • Protein Wnt-12
      Background InformationProtein Wnt-10b (Wnt-10b) is a member of the Wnt family that plays an important role in normal development such as regulation of cell fate, patterning during embryogenesis, and neoplastic transformation. Wnt-10b may promote epithelial cell differentiation and hair shaft growth, demonstrating that Wnt-10b has multiple roles in cell growth and differentiation. Mutations in Wnt-10b have been associated with an autosomal receesive disorder known as split-hand/foot malformation type 6 (SHFM6).
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human skeletal muscle tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Wnt using this rabbit polyclonal antibody, Anti-Wnt Antibody-10b validated for use in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected Wnt-10b in human skeletal muscle tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Wnt-10b.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • WNT10B
      • WNT12
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~45 kDa observed. Uncharacterized bands may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human skeletal muscle tissue lysate.

      Western Blotting Analysis: 4 µg/mL of this antibody detected Wnt-10b in 15 µg of human skeletal muscle tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN475 04053252870521

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies