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MABC95 Anti-S1PR2/EDG5 Antibody, clone 6E8.1

Anti-S1PR2/EDG5 Antibody, clone 6E8.1 detects level of S1PR2/EDG5 & has been published & validated for use in Western Blotting, IHC(P).

Anti-S1PR2/EDG5 Antibody, clone 6E8.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: S1PR2, EDG5 UniProt Number: O95136
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MABC95
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC95
      DescriptionAnti-S1PR2/EDG5 Antibody, clone 6E8.1
      Alternate Names
      • Sphingosine 1-phosphate receptor 2
      • S1P receptor 2
      • S1P2
      • Endothelial differentiation G-protein coupled receptor 5
      • Sphingosine 1-phosphate receptor Edg-5
      • S1P receptor Edg-5
      Background InformationSphingosine 1-phosphate receptor 2 (S1PR2), otherwise known as EDG5, is a ubiquitous G-protein coupled receptor for lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi, G12/13, and Gq pathways to regulate a number of second messengers and effector molecules, including cAMP, PLC, MAPK, RhoA, and Rac. S1PR2 mediates the effects of S1P on cell motility and embryonic development, among other cellular processes.
      References
      Product Information
      FormatPurified
      Control
      • Human liver tissue lysate
      PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-S1PR2/EDG5 Antibody, clone 6E8.1 detects level of S1PR2/EDG5 & has been published & validated for use in Western Blotting, IHC(P).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A representative lot detected S1PR2/EDG5 in human tonsil, liver, colorectal cancer tissues.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the cytoplasmic domain of human S1PR2/EDG5.
      EpitopeCytoplasmic domain
      Clone6E8.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody recognizes the cytoplasmic domain of S1PR2/EDG5.
      IsotypeIgMκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • S1PR2
      • EDG5
      UniProt Number
      Molecular Weight~35 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human liver tissue lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected S1PR2/EDG5 in 10 mg of human liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABC95 04053252697753

      Documentation

      Anti-S1PR2/EDG5 Antibody, clone 6E8.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-S1PR2/EDG5 Antibody, clone 6E8.1 Certificates of Analysis

      TitleLot Number
      Anti-S1PR2/EDG5, Clone 6E8.1 - 4155348 4155348
      Anti-S1PR2/EDG5, clone 6E8.1 - 2262715 2262715
      Anti-S1PR2/EDG5, clone 6E8.1 - 3403488 3403488
      Anti-S1PR2/EDG5, clone 6E8.1 - 3502139 3502139
      Anti-S1PR2/EDG5, clone 6E8.1 - 3743896 3743896
      Anti-S1PR2/EDG5, clone 6E8.1 - 4019759 4019759
      Anti-S1PR2/EDG5, clone 6E8.1 - Q2029731 Q2029731
      Anti-S1PR2/EDG5, clone 6E8.1 -2500706 2500706
      Anti-S1PR2/EDG5, clone 6E8.1 -2610508 2610508
      Anti-S1PR2/EDG5, clone 6E8.1 -2676713 2676713
      Show more

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies