Millipore Sigma Vibrant Logo

AB1532P Anti-Neurotrophin 3 Antibody

View This Product on Sigma-Aldrich
AB1532P
20 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited Availability
Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      Ch, H, RWB, IHC, FUNCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB1532P
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Neurotrophin 3 Antibody
      Alternate Names
      • NT3
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified immunoglobulin. Lyophilized from PBS, no preservatives. Reconstitute to desired volume with sterile distilled water. Suggested concentration 0.5-1 mg/mL.
      Quality LevelMQ100
      Applications
      ApplicationDetect Neurotrophin 3 using this Anti-Neurotrophin 3 Antibody validated for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Affects Function
      Application NotesImmunohistochemistry: 1-10 μg/mL (see suggested protocol).


      Immunoblotting:1-10 μg/mL


      Inhibition of biological activity in vitro: 1-10 μg/mL


      In vivo animal studies


      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenAn 11 amino acid peptide corresponding to the amino-terminal of mouse Neurotrophin 3 (NT3) coupled to BSA. The sequence is H2N-YAEHKSHRGEY-.
      HostRabbit
      SpecificityNeurotrophin 3 (NT3). Less than 0.1% cross reactivity with recombinant human BDNF, recombinant human NT4 and mouse NGF.
      Species Reactivity
      • Chicken
      • Human
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
      Gene Symbol
      • NTF3
      • NT3
      • NGF2
      • HDNF
      • MGC129711
      • NGF-2
      • NT-3
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P20783 # Seems to promotes the survival of visceral and proprioceptive sensory neurons.
      SIZE: 257 amino acids; 29355 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Brain and peripheral tissues.
      SIMILARITY: SwissProt: P20783 ## Belongs to the NGF-beta family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20 to -70°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size20 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB1532P 04053252281631

      Documentation

      Anti-Neurotrophin 3 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Neurotrophin 3 Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-NEUROTROPHIN 3 - 3191459 3191459
      RABBIT ANTI-NEUROTROPHIN 3 - 3837151 3837151
      RABBIT ANTI-NEUROTROPHIN 3 - 3873521 3873521
      RABBIT ANTI-NEUROTROPHIN 3 - 4114318 4114318
      RABBIT ANTI-NEUROTROPHIN 3 -2691392 2691392
      RABBIT ANTI-NEUROTROPHIN 3 -2736450 2736450
      RABBIT ANTI-NEUROTROPHIN 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY 3094657
      RABBIT ANTI-NEUROTROPHIN 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2953891
      RABBIT ANTI-NEUROTROPHIN 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2015532 2015532
      RABBIT ANTI-NEUROTROPHIN 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2074744 2074744

      References

      Reference overviewPub Med ID
      Anterograde trafficking of neurotrophin-3 in the adult olfactory system in vivo.
      Liu, H; Lu, M; Guthrie, KM
      Experimental neurology  241  125-37  2013

      Show Abstract
      23261763 23261763
      Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function
      Elkabes, S, et al
      J Neurosci, 16:2508-21 (1996)  1996

      8786427 8786427
      Peripheral projections of rat primary sensory neurons immunoreactive for neurotrophin 3.
      Zhou, X F and Rush, R A
      J. Comp. Neurol., 363: 69-77 (1995)  1995

      Show Abstract
      8682938 8682938
      Localization of neurotrophin-3-like immunoreactivity in the rat central nervous system.
      Zhou, X F and Rush, R A
      Brain Res., 643: 162-72 (1994)  1994

      Show Abstract
      8032912 8032912

      Related Products & Applications

      Related Products

      Catalogue Number Description  
      AB1532SP Anti-Neurotrophin 3 Antibody Show Pricing & Availability
      AB15564-200UL Anti-proNT-3 Antibody Show Pricing & Availability
      AB5583-50UL Anti-Nerve Growth Factor Antibody, pro Show Pricing & Availability
      MAB5260-60UG Anti-Nerve Growth Factor Antibody, clone 27/21 Show Pricing & Availability
      MAB5260Z Anti-Nerve Growth Factor Antibody, clone 27/21, azide free Show Pricing & Availability

      Alternative Format

      Catalogue Number Description  
      AB1532SP Anti-Neurotrophin 3 Antibody Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies